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Bambangan Seed Extract Inhibits Breast Cancer Cell Growth

Posted Apr 14 2010 7:29am
Bambangan (Mangifera pajang) is a fruit in the mango family that is native to Malaysia.  The kernel of this fruit has been shown to be rich in antioxidants like gallic acid and rutin .  A new study reports that extracts of the bambangan kernel might have breast cancer fighting properties.

In this breast cancer study , researchers cultured both hormone-dependent breast cancer cells (MCF-7 cells) and non-hormone dependent breast cancer cells (MDA-MB-231 cells) and treated them with different amounts of the bambangan seed extract.  The results of this study showed that
  • The bambangan seed extract blocked breast cancer cell growth by stopping the cell growth cycle at specific points depending on the cell line.
  • Programmed cell death of both breast cancer cell lines was stimulated by the bambangan seed extract.
  • The breast cancer cell death was induced rapidly with about 15% of the cells dying within 24 hours (non-hormone dependent breast cancer cells) and 36 hours (hormone-dependent breast cancer cells).
This new research study indicates that bambangan might have cancer fighting benefits.  Unfortunately, the phytochemicals likely to be responsible for these cancer fighting properties appear to be present mostly in the seed kernel, so it might be necessary to get the cancer fighting benefits of the bambangan by taking a supplement or consuming other fruits/vegetables with similar plant chemical content.  One option might be the mango, a relative of the bambangan and a fruit also shown to have cancer fighting properties as we discussed in a previous blog .  Other alternatives might be fruis and vegetables rich in gallic acid (walnut, blackberry, raspberry) and/or rutin (buckwheat, citrus fruits, apple peel).

To find out what my favorite breast cancer fighting foods are, read my book Fight Now: Eat & Live Proactively Against Breast Cancer at .
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