0March 5, 2010Diagnosis 4: ER+ or Estrogen Receptor Positive Breast Cancer Cells
Posted Mar 05 2010 12:00am
The cancer cells found on my breast are also ER+ or Estrogen Receptior Positive
Estrogen receptors are special proteins that the hormone estrogen binds to. Breast cancer cells that are ER+ depend on estrogen to grow. Anti-estrogen hormonal therapy blocks the receptors or reduces the amount of estrogen that can get into the receptors. As a result, the cancer cells may shrink or die.
Again, the surgical oncologist (Dr.Wong), told me that my medical oncologist (Dr. Ray mond,) may prescribe Tamoxifen.
Tamoxifen competitively inhibits the binding of estradiol to estrogen receptors, thereby preventing the receptor from binding to the estrogen-response element on DNA. The result is a reduction in DNA synthesis and cellular response to estrogen.
This again, proves that all types of cancer cells (breast/brain/bone/liver/lung) are some type of proteins. And that for it to shrink or die, some form of enzymes should bind into it so that it shrinks/gets digested/ or die.
Most women who were prescribed Tamoxifen, needs to take this drug continously for 5 years.
We also heard of a lady who have stage 3 breast cancer, who was prescribed to remove her ovaries, to stop the production of estrogen in her body. (The ovaries produce estrogen)., however, this only works for pre-menopausal women.