The Number of Electrodes Alters the Effect of DBS Surgery
Posted Sep 29 2008 1:04am
9th January 2008 - New research from Viartis, Parkinson's Disease News
Neurosurgery [2007] 61 (5 Suppl 2) : 346-355 (Temel Y, Wilbrink P, Duits A, Boon P, Tromp S, Ackermans L, van Kranen-Mastenbroek V, Weber W, Visser-Vandewalle V.)
DBS is a surgical method of greatly reducing Parkinson's Disease symptoms that uses electrodes implanted into the brain. It is still debated to what extent the techniques used affect the outcome of deep brain stimulation (DBS). Identification of the Subthalamic nucleus, which is where the surgery is often completed can be carried out using only one electrode or by using multiple electrodes. Researchers found that the simultaneous implantation of multiple electrodes does not increase the risk of bleeding or any other major intracranial complication. The use of multiple electrodes also resulted in better motor results when compared with patients who underwent DBS that was guided with a single electrode. There were significantly more improvements in patients' tremor and rigidity, and their symptom scores when using multiple electrodes. However, patients treated with multiple electrodes also showed subtle deterioration in their neuropsychological functions, particularly in memory function.
9th January 2008 - New research
from Viartis, Parkinson's Disease News
Neurosurgery [2007] 61 (5 Suppl 2) : 346-355 (Temel Y, Wilbrink P, Duits A, Boon P, Tromp S, Ackermans L, van Kranen-Mastenbroek V, Weber W, Visser-Vandewalle V.)
DBS is a surgical method of greatly reducing Parkinson's Disease symptoms that uses electrodes implanted into the brain. It is still debated to what extent the techniques used affect the outcome of deep brain stimulation (DBS). Identification of the Subthalamic nucleus, which is where the surgery is often completed can be carried out using only one electrode or by using multiple electrodes. Researchers found that the simultaneous implantation of multiple electrodes does not increase the risk of bleeding or any other major intracranial complication. The use of multiple electrodes also resulted in better motor results when compared with patients who underwent DBS that was guided with a single electrode. There were significantly more improvements in patients' tremor and rigidity, and their symptom scores when using multiple electrodes. However, patients treated with multiple electrodes also showed subtle deterioration in their neuropsychological functions, particularly in memory function.