First report of a primary intracerebral angiomatoid fibrous histiocytoma
Posted Aug 24 2008 5:59pm
The esteemed Dr. Chad DeFrain provided me with a case report from the American Journal of Surgical Pathology (2008;32:478–484) which describes the first reported case of a primary intracerebral angiomatoid fibrous histiocytoma. The relatively large tumor was located in the left occipital lobe. A team led by Dr. Arie Perry at Washington University in St. Louis describes the tumor as having a unique clear cell sarcoma-like gene fusion transcript, t(12;22). The authors conclude: "Although AFHs are usually associated with a favorable prognosis, the impact of this tumor’s atypical cerebral location and unique molecular features are unclear."