Cord Blood Improves Alzheimer’s Pathology in Mouse Model, Study Finds
Posted Aug 24 2008 5:59pm
The illustrious Dr. Doug Shevlin forwarded to me an article he found in America’s Blood Centers Newsletter which describes a study using a mouse model published online last month in the journal Stem Cells and Development . The study suggests that targeted immune suppression therapy using human umbilical cord blood cells may improve the pathology associated with Alzheimer’s disease. Researchers found that the amount of amyloid plaques – hallmarks of Alzheimer’s pathology in the brain – was reduced by 62 percent after venous infusion of umbilical cord blood. The study suggests that umbilical cord blood therapy may target the pathogenic inflammatory response that contributes to Alzheimer’s disease and other degenerative conditions in humans.
Citation : WV Nikolic , etal . Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular amyloid deposits in Alzheimer mice. Stem Cells Dev. 2008 [ Epub ahead of print]