H1N1 Vaccine, Optic Nuritis and Disseminated Encephalomyelitis
Posted Aug 12 2010 10:15am
Pediatr Infect Dis J . 2010 Aug 3. [Epub ahead of print] ADVERSE NEUROLOGIC REACTIONS AFTER BOTH DOSES OF PANDEMIC H1N1 INFLUENZA VACCINE WITH OPTIC NEURITIS AND DEMYELINATION.
Lapphra K, Huh L, Scheifele DW.
From the *Vaccine Evaluation Center, Department of Pediatrics, British Columbia Children' Hospital, University of British Columbia, Vancouver, British Columbia, Canada; and daggerDivision of Neurology, Department of Pediatrics, British Columbia Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada. Abstract
When a neurologic condition develops after vaccination of a patient, the causal relationship is difficult to determine. We report an unusual case in which neurologic signs occurred in a previously healthy child after both doses of H1N1 2009 influenza vaccine, culminating in bilateral optic neuritis and disseminated encephalomyelitis. A causal association is more likely with repeated injury following influenza vaccination.
PMID: 20686434 [PubMed - as supplied by publisher]