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Treatments For Proteinuria - Articles

VEGF inhibitors and proteinuria by Matt S. Posted Mon 15 Mar 2010 12:00am I've recently had the privilege of caring for a patient undergoing chemotherapy for a metastatic malignancy using agents targeting the vascular endothelial growth factor (VEGF) pathway. This patient, having tolerated three cycles of avastin and ipilumimab without any complications, was found on routine screening by his oncologist to have >1g/ ... Read on »
Widely Used Cancer Drug May Increase Risk For Proteinuria In Patients by Ed H. Doctor of Pharmacy Posted Tue 15 Jun 2010 5:45pm Cancer patients treated with the chemotherapy agent bevacizumab (Avastin) may be at an increased risk of severe loss of protein from the kidney into the urine that can lead to significant kidney damage and can compromise the efficacy of cancer treatment. This conclusion stems from a study of more than 12,000 patients by Shenhong Wu, M.D., Ph.D. ... Read on »
How to Treat Proteinuria in PKD by Pkd Z. Facebook Posted Wed 22 Jan 2014 6:06am Proteinuria is a sign of kidney dysfunction with the symptoms of swelling, blood urine and high blood pressure. But the quantity of leaked urine protein is not directly proportional to the degree of the kidney disease. If you have serious proteinuria, it not means that your kidney disease is also serious too. So do not be in sad earlier. How to t ... Read on »
What can We Do with Proteinuria in PKD by Pkd Z. Facebook Posted Tue 11 Feb 2014 1:56am Proteinuria, we can know from its name that there is protein in urine. The excess fluid, toxin and waste are removed from body with urine and there will be a little protein after exercise. But it is not a good thing to find a lot of protein in the urine. Why does proteinuria occur? What can we do with proteinuria?   http://www.pkdclinic.org/pk ... Read on »
So are your GP friends asking what the QoF means by proteinuria? by Dr. Donal O'Donoghue Patient Expert Posted Thu 28 May 2009 12:22am ..... if so, direct them to the BMA website that states "people with non-diabetic stage 3 to 5 CKD should have an annual test of proteinuria unless they have a previous diagnosis of proteinuria. People with diabetes already have an annual micro-albuminuria test" - and this is preceded by a statement that a lab test is required for diagnosis of p ... Read on »
Proteinuria to be added to the QOF by Dr. Donal O'Donoghue Patient Expert Posted Thu 28 May 2009 12:22am Proteinuria is expected to be added to the chronic kidney disease domain of the QOF in this financial year, ie to apply from 1 April 2008. As part of the negotiations on the General Medical Services contract for the financial year 2008/09, NHS employers have been consulting the General Practitioners Committee (GPC) on changes to the Quality ... Read on »
Proteinuria is confirmed in the QOF by Dr. Donal O'Donoghue Patient Expert Posted Thu 28 May 2009 12:22am Many people were disappointed that the original chronic kidney disease domain of the Quality and Outcomes Framework, published in early 2006, did not have proteinuria as a key indicator. In particular, the advice that all people with CKD regardless of their level of urinary protein should be treated with ACE inhibitors or angiotensin receptor bl ... Read on »
Rapamycin & Proteinuria by Matt S. Posted Tue 06 May 2008 12:00am Rapamycin (sirolimus) is a commonly used immunosupressant deriving from the bacterium Streptomyces hygroscopicus, originally found on Easter Island. It was originally developed as an antifungal agent but later found to have potent immunosuppressive and antiproliferative properties. Although effective, rapamycin has a number of unpleasant ... Read on »
Statin-induced proteinuria by Matt S. Posted Fri 25 Sep 2009 12:00am In the past I've struggled to get my head around the question of the role of statins in CKD. On the one hand they appear to slow progression, and people with lots of proteinuria often show some reduction in this measure over time. However, the effects on urinary protein excretion are at best variable, and there's no doubt that in some patients ... Read on »
The Proteinuria Controversy by Matt S. Posted Mon 28 Sep 2009 12:00am One of the largest controversies in the field of proteinuria/nephrotic syndrome research derives from a 2007 Kidney International paper published by Russo et al . Briefly stated, the authors suggest the paradigm-shifting idea that the glomerulus filters massive amounts of albumin, and that nephrotic syndrome is a defect in tubular reabsorption ... Read on »