Thalidomide Approved for Myeloma Treatment
by
Teresa K.Posted
Wed 14 Jan 2009 8:35pm
Big news in the myeloma world on Friday! Thalidomide was approved by the FDA for treatment of multiple myeloma. Thalidomide is an old drug with a dark past. Thalidomide was introduced in 1956 by Chemie Grunenthal, a West German pharmaceutical company. In Europe in the early 1960s, thalidomide was prescribed for insomnia for adults and to pregnant women
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Thalidomide
by
Teresa K.Posted
Wed 14 Jan 2009 8:36pm
By the end of 2001, the myeloma beast was rising again. The transplant bought us about seven months. Worth it or not? Who can say? The next therapy was thalidomide. Thalidomide is an old drug with an interesting history. It was originally prescribed in Europe in the 1950s and 60s as a sedative. Pregnant women who took it had babies with deformities
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Thalidomide for angiodysplasia
by
Mark LevinPosted
Mon 02 Aug 2010 6:06pm
Angiodysplasias are the cause of GI bleeding in 3–6% of all patients and a common cause of beeeding in the elderly. Thalidomide uas been reproted in a number of case reports qnd case series to reduce the angiodysplasias and GI bleeding. However no prospective studies have been done. The drug is now in a clinical trial: Thalidomide Reduces
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New Insights into Thalidomide
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Environmental HealthPosted
Sat 31 Jan 2009 9:00pm
New Insights into Thalidomide
Formal Correction: This article has been formally corrected to address.... New Insights into Thalidomide. Environ Health Perspect 117:A61-A61.
doi:10.1289/ehp.117-a61
Thalidomide, a drug banned in some countries for nearly 50 years
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Thalidomide for angiodysplasia
by
Mark LevinPosted
Mon 21 Dec 2009 1:41pm
and increases vessel permeability. GI angiodysplasias are characterized by elevated serum levels of VEGF and thalidomide can potentially affect them. In addition, colonic angiodysplasias... reports of the use of thalidomide for this condition but no prospective studies. There are also case reports and series of this use in other GI bleeding conditions
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I. What Thalidomide Gave Us
by
Teresa K.Posted
Wed 14 Jan 2009 8:36pm
As I said, thalidomide gave Richard an almost three year remission. Many of the posts on the MMA mailing list or ACOR mailing list are very critical of thalidomide. Richard has numbness in his fingers and feet that likely will be permanent. He had ongoing problems with constipation and he feels that his thinking was fuzzy while he took thalidomideRead on »
II. What Thalidomide Gave Us
by
Teresa K.Posted
Wed 14 Jan 2009 8:36pm
25. Sister Sarah was so proud!
Again, I just have to say again that without thalidomide all these great times would not have been possible.
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Thalidomide and Revlimid for myelofibrosis
by
Mark LevinPosted
Wed 24 Jun 2009 7:01pm
There are a number of studies suggesting that thalidomide with or without prednisone can ameliorate cytopenias of myelofibrosis with or withotu myelod metaplasia, although..., hydroxyurea, and splenectomy. Single agent thalidomide has been associated with significant palliative effects in patients with myeloid metaplasia including improvement in blood counts
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Thalidomide/Dex
by
Lori P.Posted
Wed 22 Jul 2009 8:08pm
refer patients to Little Rock, you are put on some sort of "oral" chemotherapy in the interim before SCT. ( Stem Cell Transplant )
Thalidomide is the drug given to women... and did all we could to suck it up and let it go. It was not easy.
The Thalidomide made him tired and he would take it at night. The dex was like speed, so he would take
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