All about Tamoxifen
by
Cathy T.Posted
Wed 01 Oct 2008 8:20pmTamoxifen (Nolvadex®) is an anti-estrogen medication that was developed about 30 years ago and has been used to treat some types of breast cancer for the last 20 years or so. It is taken by mouth.
Read article here
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The role of CYPD6 inhibitors with tamoxifen
by
Mark Pool, MDPosted
Thu 13 Aug 2009 12:00am
I have seen a few requests for send-out genotype testing for CYPD6, the cytochrome P450 enzyme in localized to the liver that converts tamoxifen to its active... of CYPD6 inhibitors on breast cancer recurrence in patients receiving tamoxifen.
Both of these studies have significant methodological problems that limit the significance
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Tamoxifen on hold
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LesaPosted
Mon 01 Sep 2008 7:11pm
I am feeling much ambivalence towards the Tamoxifen.
I have cut off my breast, poisened and burned my body and if that hasn't killed the cancer.......?
I did not have a problem doing chemo and radiation and Herceptin for short periods. But Tamoxifen daily for 5 years? It does not sit well with me.
Chemicals - chemicals - chemicals
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Acupuncture Reduces Tamoxifen-Induced Hot Flashes by Half
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Cathy T.Posted
Sun 24 Aug 2008 3:36pm
Knowing that acupuncture provides effective relief from hot flashes and other symptoms associated with menopause, Jill Hervik, a physiotherapist and acupuncturist, conducted a trial to see if the same relief could be achieved in breast cancer patients taking tamoxifen after surgery for estrogen-sensitive breast cancers. Tamoxifen causes some
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Stopping Tamoxifen (again)
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LesaPosted
Wed 06 May 2009 10:10pm1 Comment
Yup. I am quitting it again.
My joints are acting up again. I got off the treadmill an hour ago and the bottom of my feet are throbbing. Hot flashes have amped up as well.
No more. Too uncomfortable.
Plus I have put on a healthy 10 pounds-ish since starting the Tamoxifen so I am going to blame the medicine instead of my enjoyment
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Paxil Blocks Tamoxifen, Lowers S ...
by
Dr. Rubens D.Posted
Sun 21 Feb 2010 7:59am
Paxil Blocks Tamoxifen, Lowers Survival Odds Against Breast Cancer
21 feb 2010-- Women with breast cancer who take both tamoxifen and the antidepressant Paxil may increase their risk of dying because Paxil reduces tamoxifen's effectiveness, Canadian researchers report.
"Paxil can deprive women of the benefit of tamoxifen, especially when it is used
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Tamoxifen & 2D6 Genes
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Lisa E. L.Posted
Thu 19 Nov 2009 10:02pm
regarding 2D6 gene variants and response to the breast cancer drug, tamoxifen, and whether this research warrants any warnings or changes to the tamoxifen package insert.
Here’s a link to the FDA’s Executive Summary on Tamoxifen and 2D6. (Clicking this link will download a .PDF.)
In concert with the hearing, DNA Direct is launching our first drug
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Tamoxifen, Genes and Efficacy Rates
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Lisa E. L.Posted
Thu 19 Nov 2009 10:02pm
of tamoxifen efficacy and genotype.
Much has been made of research published in the past few months regarding aromatase inhibitors — to what degree they prevent breast cancer recurrence, long-term survival, overall survival, and to what degree they’re better than tamoxifen (current studies indicate ~2-3%). That’s very exciting.
What you’re not hearing about
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Tamoxifen & Zoloft bad cocktail
by
LesaPosted
Sun 18 Oct 2009 10:00pm
New Study: Antidepressants Commonly Prescribed with Tamoxifen Put Women at Much Higher Risk for Recurrent Breast Cancer:
- Several SSRIs more than double risk of cancer recurrence in tamoxifen
treated patients
- Nearly 30 percent of tamoxifen users take drugs that reduce its
effectiveness against breast cancer
ORLANDO, Fla., May
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