Systemic Lupus Erythematosus - Articles

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UCB and Immunomedics announce positive results for epratuzumab phase IIb study in systemic lupus... by Duane P. Patient Expert

UCB and Immunomedics announced on Friday top-line results from a Phase IIb clinical study which compared the effect of the drug candidate epratuzumab to placebo in people with systemic lupus. The data showed that the 12-week dose response and the dose frequency study of epratuzumab in patients with moderate to severe active lupus demonstrated a cli ... Read on »

UCB and Immunomedics announce positive results for epratuzumab phase IIb study in systemic lupus... by Wick D. UCB and Immunomedics announced on Friday top-line results from a Phase IIb clinical study which compared the effect of the drug candidate epratuzumab to placebo in people with systemic lupus. The data showed that the 12-week dose response and the dose frequency study of epratuzumab in patients with moderate to severe active lupus demonstrated a cli ... Read on »

Anxiety News: Anxiety And Depression Lower Quality Of Life In Majority Of Systemic Lupus... by Katie G. Healthy Living Professional

Anxiety And Depression Lower Quality Of Life In Majority Of Systemic Lupus Erythematosus Patients ScienceDaily (June 12, 2009) — 92.8% of patients with systemic lupus erythematosus (SLE) suffer anxiety and depression which signif ... Read on »

Sicca symptoms in Thai patients with rheumatoid arthritis, systemic lupus erythematosus and... by Jan

Research by Wangkaew S. and Colleague. This study was performed to determine the prevalence of ocular and oral sicca symptoms in Thai patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and scleroderma (Scl). The ocular symptoms and sign (the Schirmer's 1 test) and the oral sicca symptoms and sign (the Saxon's test) in eac ... Read on »

OxLDL/β2GPI Complexes and Autoantibodies in Patients with Systemic Lupus Erythematosus,... by Jan

... IgG, and IgM anti-oxLDL/β2GPI antibodies were measured using enzyme-linked immunosorbent assay (ELISA). Measurements were taken in two patient groups: (1) those with systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and rheumatoid arthritis (RA); and (2) those with primary and secondary antiphospholipid syndrome (APS). For oxL ... Read on »

OxLDL/β2GPI Complexes and Autoantibodies in Patients with Systemic Lupus Erythematosus,... by Jan

... gG, and IgM anti-oxLDL/β2GPI antibodies were measured using enzyme-linked immunosorbent assay (ELISA). Measurements were taken in two patient groups: (1) those with systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and rheumatoid arthritis (RA); and (2) those with primary and secondary antiphospholipid syndrome (APS). For oxLD ... Read on »

The progressive systemic sclerosis/systemic lupus overlap: an unusual clinical progression. by Jan

By R. A. Asherson and Colleague. Three patients with the unusual combinations of discoid lupus, systemic lupus erythematosus (SLE), and progressive systemic sclerosis (PSS) are reported. The first patient developed PSS eight years after a diagnosis of discoid lupus had b ... Read on »

Valvular and coronary heart disease in systemic inflammatory diseases by Jan

Valvular and coronary heart disease in systemic inflammatory diseasesBy Carlos A RoldanSystemic lupus erythematosus (SLE), primary antiphospholipid syndrome (PAPS), rheumatoid arthritis (RA), ankylosing spondylitis (AKS), and scleroderma are immune mediated infl ... Read on »

Reactive Oxygen Species Modified Polyguanylic Acid: Immunogenicity and Implications for Systemic... by Jan

... D.K.; Ali R. Abstract: The effect of the hydroxyl radical on polyguanylic acid [poly(G)] was investigated with regard to progressive increase of autoantibodies against it in systemic lupus erythematosus (SLE) and progressive systemic sclerosis (PSS). Rabbits immunized with both native and ROS-poly(G) induced high titre antibodies. Immune IgG exhib ... Read on »

KGO-TV Story Highlights LFA-Supported Lupus Investigator by Duane P. Patient Expert

... proved by the U.S. Food and Drug Administration (FDA) specifically for lupus.Watch the KGO story about lupus.About Dr. Utz’s LFA Research Grant -- "Proteomic Studies in Systemic Lupus Erythematosus"Lay Abstract:Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease that can progressively damage multiple organs. The pathophys ... Read on »