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Sle Discoid - Articles

Systemic lupus erythematosus (SLE) by Ahmad.H Posted Fri 03 Dec 2010 12:00am SLE is a chronic disease that causes inflammation of connective tissue. It is a multisystem autoimmune inflammatory disease. SLE is the commonest and the most serious type of lupus.  What causes SLE ? SLE is believed to be an autoimmune disease, which means that the body's immune system produce antibodies that attacks the own ... Read on »
UCB and Immunomedics announce positive results for epratuzumab phase IIb study in systemic lupus erythematosus (SLE) by Duane P. Patient Expert Posted Mon 31 Aug 2009 10:08pm 1 Comment UCB and Immunomedics announced on Friday top-line results from a Phase IIb clinical study which compared the effect of the drug candidate epratuzumab to placebo in people with systemic lupus. The data showed that the 12-week dose response and the dose frequency study of epratuzumab in patients with moderate to severe active lupus demonstrated a clinically Read on »
UCB and Immunomedics announce positive results for epratuzumab phase IIb study in systemic lupus erythematosus (SLE) by Wick D. Posted Mon 31 Aug 2009 6:58am UCB and Immunomedics announced on Friday top-line results from a Phase IIb clinical study which compared the effect of the drug candidate epratuzumab to placebo in people with systemic lupus. The data showed that the 12-week dose response and the dose frequency study of epratuzumab in patients with moderate to severe active lupus demonstrated a clinically Read on »
OxLDL/β2GPI Complexes and Autoantibodies in Patients with Systemic Lupus Erythematosus, Systemic Sclerosis, and Antiphospho by Jan Posted Fri 11 Sep 2009 4:56pm immunosorbent assay (ELISA). Measurements were taken in two patient groups: (1) those with systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and rheumatoid arthritis (RA); and (2) those with primary and secondary antiphospholipid syndrome (APS). For oxLDL/β2GPI complexes, SLE and SSc patients had the highest mean optical densities (ODs) ( P Read on »
OxLDL/β2GPI Complexes and Autoantibodies in Patients with Systemic Lupus Erythematosus, Systemic Sclerosis, and Antiphospho by Jan Posted Fri 11 Sep 2009 4:56pm assay (ELISA). Measurements were taken in two patient groups: (1) those with systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and rheumatoid arthritis (RA); and (2) those with primary and secondary antiphospholipid syndrome (APS). For oxLDL/β2GPI complexes, SLE and SSc patients had the highest mean optical densities (ODs) ( P < .001 Read on »
New Data Shows Epratuzumab Provided Significant Efficacy for Patients with Moderate to Severe Systemic Lupus Erythematosus by Duane P. Patient Expert Posted Wed 16 Jun 2010 9:02am UCB and Immunomedics Inc. announced today that a new lupus drug candidate, epratuzumab, provided a significant reduction in disease activity in patients with moderate to severe active systemic lupus erythematosus (SLE). Findings demonstrate that in a patient population with predominantly severe disease activity, epratuzumab is improving patients Read on »
New Data Shows Epratuzumab Provided Significant Efficacy for Patients with Moderate to Severe Systemic Lupus Erythematosus by Wick D. Posted Wed 16 Jun 2010 12:10pm UCB and Immunomedics Inc. announced today that a new lupus drug candidate, epratuzumab, provided a significant reduction in disease activity in patients with moderate to severe active systemic lupus erythematosus (SLE). Findings demonstrate that in a patient population with predominantly severe disease activity, epratuzumab is improving Read on »
Anxiety News: Anxiety And Depression Lower Quality Of Life In Majority Of Systemic Lupus Erythematosus Patients by Katie G. Healthy Living Professional Posted Wed 17 Jun 2009 6:31pm Anxiety And Depression Lower Quality Of Life In Majority Of Systemic Lupus Erythematosus Patients ScienceDaily (June 12, 2009) — 92.8% of patients with systemic lupus erythematosus (SLE) suffer anxiety and depression which significantly affects both their physical and emotional quality of life (QoL), according to the results of a new study presented Read on »
Sicca symptoms in Thai patients with rheumatoid arthritis, systemic lupus erythematosus and scleroderma: a comparison with age-m by Jan Posted Fri 11 Sep 2009 4:58pm (RA), systemic lupus erythematosus (SLE), and scleroderma (Scl). The ocular symptoms and sign (the Schirmer's 1 test) and the oral sicca symptoms and sign (the Saxon's test) in each of 50 RA, SLE and Scl patients were compared with their age-matched controls. The correlation between the presence of sicca symptoms and signs with their clinical activity Read on »
Involvement of the eye in SLE and scleroderma. A study using fluorescein angiography in addition to clinical ophthalmic assessme by Jan Posted Fri 11 Sep 2009 4:56pm By D M Grennan and J Forrester General examination of the eye was carried out in 22 patients with systemic lupus erythematosus (SLE) and in 10 with scleroderma. 3 of the SLE and 2 of the scleroderma patients had keratoconjunctivitis sicca. Fluorescein angiography showed abnormalities of the retinal vasculature in one of a subgroup of 12 SLE Read on »