Selenium and the Methionine Sulfoxide Reductase System
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JanPosted
Wed 11 Nov 2009 10:03pm
in the enzymatic activity efficiency of selenoproteines. The methionine sulfoxide reductase (Msr) system that reduces methionine sulfoxide (MetO) to methionine comprises the selenoprotein... sulfoxide reductase (MsrB) protein level in certain mouse tissues
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medium chain acylcoenzyme A dehydrogenase deficiency
by
Martin EastwoodPosted
Wed 24 Jun 2009 2:05pm
Newborn screening in England and Northem Ireland includes screening for medium chain acylcoenzyme A dehydrogenase (MCAD) deficiency within the entire newborn population. M CAD deficiency is the most common inherited disorder of mitochondrial fatty acid oxidation in people from northern Europe. This autosomal recessive metabolic disease affects
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Glucose 6 phosphate dehydrogenase deficiency
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pathologystudentPosted
Fri 31 Jul 2009 11:55am
Next in our little series on hereditary hemolytic anemias is glucose 6 phosphate dehydrogenase (or G6PD) deficiency.
Before we get into G6PD deficiency, we need to discuss just what this G6PD enzyme does. If you can close your eyes and try to think back to biochemistry, see if you can recall something called glutathione (if you can’t, look
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Isocitrate Dehydrogenase 1 (IDH1) R132 Mutation Human Melanoma Metastasis Cell Line
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nih.govPosted
Thu 25 Nov 2010 7:00pm
Description of Invention:
Isocitrate dehydrogenase 1 (IDH1) plays an important role in glucose metabolism in the cytoplasm, converting isocitrate to alpha-ketoglutarate while reducing nicotinamide adenine dinucleotide phosphate (NADP+ to NADPH). However, when IDH1 harbors a R132 mutation it results in the accumulation of 2-hydroxyglutarate
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Discontinuing Drugs for BPH May ...
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Dr. Rubens D.Posted
Sat 25 Apr 2009 11:34pm
doses of one of the uroselective α-blockers alfuzocin or tamsulosin, plus the 5α-reductase inhibitors finasteride (5 milligrams) or dutasteride (0.5 milligrams).
The researchers... of 5α-reductase inhibitors during combination therapy induces prostate regrowth, as well as aggravation of symptoms in men with BPH," Jeong and colleagues conclude. "This result, therefore
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Neuropathologist provides alternate explanation for child death in Colorado abuse case
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Dr. Brian M.Posted
Tue 10 Feb 2009 10:12am
with his lawyers) declined to testify in his trial today. Dr. Cohen stated that the 11-week-old infant suffered from methylenetetrahydrofolate reductase deficiency, an autosomal... methylenetetrahydrofolate reductase (MTHFR) deficiency: A case report of nonclassical homocysteinuria.Journal of Child Neurology. Volume 23, Number 7. July 2008, p 823-828.
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New drug for BPH to contain dutasteride; will affect PSA assessment
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Dr. Arnon KrongradPosted
Tue 15 Jun 2010 12:00am
their perceived risk for prostate cancer.
Both of the approved 5α-reductase inhibitors (finasteride and dutasteride) have the ability to drive down a man’s PSA level, making it look as though his PSA level is well within the normal range, although the patient’s actual PSA level if he were not receiving a 5α-reductase inhibitor his PSA might actually be twice
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Drugs for Prostate Cancer Preven ...
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Dr. Rubens D.Posted
Tue 03 Mar 2009 2:53pm
from a discussion" of the benefits and potential risks of using 5-alpha-reductase inhibitors, including finasteride and dutasteride, for preventing prostate cancer, the Journal...-reductase inhibitors for chemoprevention, physicians should explain that:
the drugs do not eliminate the risk for prostate cancer;
the risk for high-grade prostate cancer
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