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Prostate Cancer Gleason Score - Articles

Prostate Cancer Surgery after a Steep Gleason Score Jump by Rabbi Ed . Posted Sun 16 Aug 2009 11:03pm Q: My biopsy Gleason score recently jumped to a 9 (out of 10), so there's no question my prostate cancer is more aggressive than I thought it was. I've decided to have robotic surgery. How likely is it that I'll have a prostate cancer recurrence some time after my cancerous prostate is removed? -D. A: I'm sorry to hear the  bad news ... Read on »
Gleason score and risk of death from prostate cancer by Dr. Arnon Krongrad Medical Doctor Posted Sun 28 Sep 2008 7:03pm Based on a reanalysis of prostate cancer data from the Connecticut tumor registry, Albertsen writes in the World Journal of Urology that, “high risk prostate cancer is best identified by Gleason score 7-10.” However, he further concludes that there is no evidence to support the suggestion that “men with high-grade disease are less likely to b ... Read on »
Fox Chase study finds Gleason scores better predict prostate cancer's recurrence after radiation: by Cancer.gov Posted Sat 08 Oct 2011 11:37pm Fox Chase study finds Gleason scores better predict prostate cancer's recurrence after radiation: NCI Cancer Center News In a new Fox Chase Cancer Center study, researchers have found that Gleason scores determined by pathologists at Fox Chase Cancer Center more accurately predict the risk of recurrence than Gleason scores from refer ... Read on »
Is surgery appropriate for men with Gleason 8-10 disease? by Dr. Arnon Krongrad Medical Doctor Posted Fri 12 Dec 2008 3:39pm It is well known that a Gleason score of 8-10 at the time of diagnosis is predictive of less good long-term outcomes in the treatment of prostate cancer. However, it is also well known that many men who present with early stage prostate cancer and a Gleason score of 8-10 do very well following radical surgery. A Spanish group ( Rioja Zuaz ... Read on »
Brachytherapy outcomes for Gleason 7 patients by primary grade by Dr. Arnon Krongrad Medical Doctor Posted Fri 16 Apr 2010 12:00am A new article from a group in the UK suggests that there is no difference in outcomes between patients with localized disease and with Gleason scores of 4 + 3 = 7 or 3 + 4 = 7 when their PSA is ≤ 10 and they are treated with iodine-125-based, permanent seed brachytherapy. Monroe et al. report data on the outcomes of 187 ... Read on »
Surveillance of Older Men with Low-Risk Cancer of the Prostate by Bruce Friedman Patient Expert Posted Wed 04 May 2011 12:00am A gnarly problem for patients with a low-risk cancer of the prostate is whether to opt for surgery and also what constitutes adequate monitoring if they do not undergo surgery (see: Solid Advice for Older Men Regarding PSA Screening for Prostate Cancer ). A recent article address this issue in a very clear fashion (see: Closely Monit ... Read on »
The aggressive treatment of high-risk localized and node-positive prostate cancer by Dr. Arnon Krongrad Medical Doctor Posted Mon 29 Nov 2010 12:00am Long-term follow-up data have just been published from two studies designed to provide preliminary information on the potential use of very aggressive forms of treatment in men with high-risk categories of prostate cancer. In the first of these reports, Dibiase et al. offer us data from a prospective, Phase II trial of androgen ... Read on »
Prostate Cancer Treatment - Is Surgery Right for You? - Part I by Rabbi Ed . Posted Wed 01 Sep 2010 12:00am Choosing the best prostate cancer treatment is a complex matter. For that reason I’d like to review some treatment options in a two-part series, starting with the material below.  I invite you to share your experiences and views in the comment section after the second part of this dialogue, which I’ll post tomorrow. Prost ... Read on »
Cell cycle regulation and aggressive forms of prostate cancer by Dr. Arnon Krongrad Medical Doctor Posted Sat 02 Jan 2010 12:00am A new paper by Wang et al. in a recent issue of Cancer Research has proposed details of a specific connection between control over the growth and division of prostate cancer cells and clinical occurrence of the more aggressive forms of prostate cancer. In itself, this is not a surprising idea. After all, all cance ... Read on »
Chili pepper product slows PSA doubling time in prostate cancer patient by Dr. Arnon Krongrad Medical Doctor Posted Mon 08 Mar 2010 12:00am Several years ago (2006 to be precise) it was reported by Mori et al. and by Sánchez et al. that capsaicin (the strong-smelling, active component of chili peppers) was able to kill prostate cancer cells in mouse-based cell cultures. In an article published in February, Jankovic et al. have described what they claim to ... Read on »