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Neoplasm Tumor - Articles

What is the relative prevalence of CNS metastases versus primary tumors?: Simple question, complex answer by Dr. Brian M. Medical DoctorHealth Maven Posted Mon 08 Mar 2010 4:14pm During the pre-exam pathology review session at my medical school, one of the students asked about the relative incidence of metastases to the CNS versus primary CNS neoplasms. I answered that metastases are ten times more common than primary tumors. After the presentation, a colleague in the audience pointed out to me that the current issue of ... Read on »
Genetics Home Reference: gastrointestinal stromal tumor by Posted Wed 21 Dec 2011 12:20pm On this page: Description Genetic changes Inheritance Treatment Additional information Other names Glossary definitions Reviewed December 2011 What is gastrointestinal stromal tumor? A gastrointestinal stromal tumor (GIST) is a type ... Read on »
Childhood Cancer Survivors at Greater Risk for Tumors as Adults by HealthFinder Posted Tue 07 Jun 2011 1:00pm healthnewslink Early exposure to pelvic radiation ups the risk of subsequent tumors in that region, study finds. ... Read on »
What's on your tumor biomarker wish list? by Dr. Brian M. Medical DoctorHealth Maven Posted Fri 16 Aug 2013 11:06am Photo courtesy of Shellie Sherrod The College of American Pathologists Neuropathology Committee (pictured, minus the illustrious Dr. Aaron Wagner ) poses the following question to the neuropathology community worldwide "If you were constructing a panel of eight biomarkers there were well-established prognostic/predictive markers ... Read on »
Relatives of people with brain tumors at higher risk for developing the same type of tumor by Kathlyn S. Patient Expert Posted Wed 01 Oct 2008 5:07pm A new study by researchers at the University of Utah found that people with a family history of cancerous brain tumors appear to be at higher risk of developing the same kind of tumors compared to people with no such family history. The researchers reviewed the medical records of 1,401 people from Utah with primary brain tumors -- either gliob ... Read on »
MUC-1 Tumor Antigen Agonist Epitopes for Enhancing T-cell Responses to Human Tumors by Posted Mon 26 Mar 2012 8:00pm Description of Invention: The MUC-1 tumor associated antigen has been shown to be overexpressed and/or underglycosylated in a wide range of human cancers. The C-terminus region of MUC-1 (MUC-1C) has been shown to be an oncogene and has been associated with a more aggressive phenotype in several different cancers. Scienti ... Read on »
Cell Phones Not Linked to Brain Tumors in Children by Poh Tin Tan Posted Mon 08 Aug 2011 10:50pm From Medscape Education Clinical Briefs News Author: Roxanne Nelson CME Author: Charles P. Vega, MD 07/29/2011; The possibility of a higher risk for brain tumors related to the use of mobile phones is truly frightening, particularly if such a risk applies to children and adolescents as well as to adults. The current study by Röösli and c ... Read on »
Gleevec for follicular dendritic cell tumor by Mark Levin Posted Wed 24 Jun 2009 7:01pm Follicular dendritic cell sarcoma is a rare, malignant, non-lymphoid cell-derived tumor that originates from B-lymphoid follicles of nodal and extranodal sites. These rare tumors form a spectrum within a rare and difficult to diagnose category of diseases known as histiocytic and dendritic cell neoplasms. It has been reported in around 100 case ... Read on »
Tumor speciation by Mark Pool, MD Posted Tue 10 Mar 2009 12:00am Dr. Jules Berman recently blogged about tumor speciation which not only is a brief summary of his book Neoplasms: Principles of Development and Diversity but also frames a discussion of the important question of why are there different types (species) of recognizable tumors in specific anatomical sites yet each individual tumor withi ... Read on »
ALK Inhibition in Non-Small Cell Lung Cancer and Inflammatory Myofibroblastic Tumor by Mark Pool, MD Posted Thu 28 Oct 2010 9:51pm Great stuff in this week's NEJM! Today's (October 28, 2010) New England Journal of Medicine has no less than three articles reporting the use of small molecule ALK tyrosine kinase inhibitor crizotinib (PF-02341066, Pfizer) in non-small-cell lung cancers harboring the oncogenic fusion gene EML4-ALK and in a patient with ALK-rearrangemen ... Read on »