Myelodysplastic Syndrome - Articles

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Danazol for myelodysplastic syndrome by Mark Levin Posted Sun 26 Sep 2010 4:25am for Thrombocytopenia in Patients with Myelodysplastic Syndromes Acta Haematol 2002;107:234-236 Cheson, Bruce D. The Myelodysplastic Syndromes Oncologist 1997 2: 28-39 ... and Aranesp have largely supplanted Danazol. In the past, it has often been used in myelodysplasia for anemia. However, most supporting evidence is old and not rigorous. I searched Read on »

Cyclacel Drug Promising in Myelodysplastic Syndrome by Medline Plus Posted Sat 04 Dec 2010 5:30pm with the blood cancer myelodysplastic syndrome who were not helped by prior treatment survived for one year after taking an experimental drug being developed by Cyclacel Pharmaceuticals... in a statement. "Myelodysplastic syndrome patients have a poor outcome after treatment failures of hypomethylating agents. Effective therapies Read on »

Cytogenetics in Myelodysplasia by Mark Levin Posted Mon 01 Mar 2010 10:17pm The biologic and clinical relevance of cytogenetic analysis in myelodysplastic syndromes (MDS) is well established and karyotype has been identified by the International... of cytogenetics on the course of myelodysplasia.Curr Treat Options Oncol. 2007 Apr;8(2):117-28. nccn.org, myelodysplastic Read on »

Juvenile Myelomonocytic Leukemia by Mark Levin Posted Wed 08 Dec 2010 6:17pm Smith FO, Loh ML. Myelodysplastic and myeloproliferative syndrome in children. In: Hoffman R, Benz EJ, Shattil SJ, Furie B, Silberstein LE, McGlave P, et al., editors. Hematology: basic principles and practice. 5th ed. Philadelphia (PA): Churchill Livingstone; 2008. Juvenile myelomonocytic leukemia is a type of a myelodysplastic syndrome. The only Read on »

Vidaza Maintenance in AML by Mark Levin Posted Tue 03 Aug 2010 6:44pm ) with intermediate-2 and high-risk myelodysplastic syndrome (MDS), chronic myelomonocytic leukaemia (CMML) or acute myeloid leukaemia (AML). Michael Grövdal et al, Maintenance treatment with azacytidine for patients with high-risk myelodysplastic syndromes (MDS) or acute myeloid leukaemia following MDS in complete remission after induction chemotherapy, B ritish Journal Read on »

Acute leukemia quiz by pathologystudent Posted Fri 20 Nov 2009 10:02pm % myeloblasts and some funny-looking neutrophils and precursors. The most likely diagnosis is: A. Acute myeloid leukemia B. Acute lymphoblastic leukemia C. Myelodysplastic syndrome... infection B. No disease, unless 20% of the nucleated cells have Auer rods C. A myelodysplastic syndrome D. Acute myeloid leukemia E. Acute lymphoblastic leukemia 6. Acute Read on »

Revlimid for AML with 13q abnormality. by Mark Levin Posted Sat 21 Nov 2009 10:02pm with myelodysplastic syndromes (MDS). The U.S. Food and Drug Administration has approved Revlimid for the treatment of low- to intermediate-risk MDS in patients who are transfusion-dependent... and Myelodysplastic Syndrome This study is currently recruiting participants. Verified by M.D. Anderson Cancer Center, July 2009 First Received: August 4, 2006 Last Updated: July 30, 2009 Read on »

Revlimid for Hodgkin's by Mark Levin Posted Mon 25 Oct 2010 9:42am of myelodysplastic syndromes (MDS) wih a 5q- mutation and for first line treatment of multiple myeloma in conjunction with dexamethasone. The only publisehd reprot that I could find was of 12 Read on »

Rhadoid Tumor Predisposition Syndrome: A recently defined genetic syndrome by Dr. Brian M. Medical Doctor

Posted Mon 19 Jan 2009 1:19am

1 Comment that the WHO consensus committee also recognized a new genetic syndrome got lost in the mix. Here's the scoop on the new syndrome: Rhabdoid Tumor Predisposition Syndrome (RTPS... and early childhood. The atypical teratoid/rhabdoid tumor (AT/RT) is by far the most common CNS malignacy associated with this syndrome. Up to one-third of AT/RTs are thought to arise Read on »

Nuts Combat Metabolic Syndrome (Syndrome X) by Dr. Gabe M. Medical Doctor

Posted Mon 29 Dec 2008 4:37pm to a Mediterranean diet helps to reverse Metabolic syndrome, defined as having three or more of the following: 1) abdominal obesity, 2) high triglycerides, 3) low HDL (good) cholesterol, 4) high blood sugar and 5) high blood pressure. More than 20 percent of North Americans have metabolic syndrome and are at high risk for diabetes. Many of these people will die Read on »