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Monocytes of Patients with Systemic Sclerosis (Scleroderma) Spontaneously Release In Vitro Increased Amounts of Superoxide Anion by Jan Posted Fri 11 Sep 2009 4:59pm monocytes and polymorphonucleate neutrophils of SSc patients to generate superoxide anion (O2–); and (ii) to investigate whether the O2– produced by these cells involved... the generation of O2–, unmanipulated monocytes of SSc patients generated more O2– than primary Raynaud's phenomenon patients and normal control monocytes (p= 0.0001), and the release Read on »
Methods and Compositions for Making Dendritic Cells from Expanded Populations of Monocytes and for Activating T Cells by nih.gov Posted Mon 30 Jun 2008 5:00pm significantly enhances the generation of human dendritic cells from peripheral blood monocytes making possible more extensive use and study of this unique cell population and thereby... Description of Invention: The current invention embodies methods for easily generating large numbers of dendritic cells from IL-3 cultured populations of monocytes Read on »
Chemokine expression by systemic sclerosis fibroblasts: Abnormal regulation of monocyte chemoattractant protein 1 expression by Jan Posted Fri 11 Sep 2009 4:55pm RNA (mRNA) for different C-C and C-X-C chemokines by SSc and normal fibroblasts was studied by RNase protection assay. Monocyte chemoattractant protein 1 (MCP-1) protein production was analyzed by enzyme-linked immunosorbent assay. The chemotactic effect of fibroblast-derived MCP-1 on monocytic cells was analyzed in a transmigration assay. Nuclear Read on »
The impact of high anxiety level on the oxidative status of mouse peripheral blood lymphocytes, granulocytes and monocytes by Leslie M. Healthy Living Professional Posted Mon 17 Nov 2008 9:19pm , granulocytes and monocytes from the peripheral blood of mice by using a 2',7'-dichlorofluorescein diacetate (DCFH-DA) probe. The behavioural light/dark choice test was used... lymphocytes, granulocytes and monocytes. PMID: 18593579 [PubMed - as supplied by publisher] Read on »
Serum levels of monocyte chemotactic protein-3/CCL7 are raised in patients with systemic sclerosis: association with extent of s by Jan Posted Sun 05 Dec 2010 9:00pm Objective: To determine serum levels of monocyte chemotactic protein-3 (MCP-3) and its clinical associations in patients with systemic sclerosis (SSc). Methods: Serum MCP-3 levels from 69 patients with SSc were examined by ELISA. Results: Serum MCP-3 levels were raised in patients with SSc (n = 69) compared with healthy controls (n Read on »
Normal Monocyte And Fibrocyte Behavior In Scleroderma Is Restored By Caveolin-1 Scaffolding Domain (CSD) Peptide: Implications F by Jan Posted Mon 21 Mar 2011 8:35am the accepted importance of the contribution of monocyte-derived fibrocytes in the development of lung fibrosis, their role in scleroderma is not clear. The aim of this study was to investigate the role of caveolin-1 on monocyte and fibrocyte migration into injured lung tissue in scleroderma and in the animal model of bleomycin-induced lung fibrosis. Methods Read on »
Immunomodulatory effects of vitamin D on monocyte-derived dendritic cells in multiple sclerosis by stuart Patient Expert Posted Fri 22 Oct 2010 12:00am In order to evaluate the effects of vitamin D3 on monocyte-derived dendritic cells (DCs) of relapsing–remitting multiple sclerosis patients, DCs differentiation and maturation were evaluated in vitro based on surface phenotypic changes. The expression of CD14, CD83, CD1a, CD80, CD86, CD206 and C209 was analysed by fluorescence-activated cell Read on »
Lycopene inhibits TNF-alpha-induced endothelial ICAM-1 expression and monocyte-endothelial adhesion. by Jan Posted Sat 10 Jul 2010 12:00am pathway. In a functional study, lycopene dose-dependently attenuated monocyte adhesion to endothelial monolayer but not that adhesion to extracellular matrix. Taken together, we provided here the first evidence showing that lycopene is able to inhibit TNF-alpha-induced NF-kappaB activation, ICAM-1 expression, and monocyte-endothelial interaction, suggesting Read on »
Copper-dependent antioxidase defenses in inflammatory and autoimmune rheumatic diseases by Jan Posted Fri 11 Sep 2009 4:56pm , was monitored by electron paramagnetic resonance in the presence of activated neutrophils and monocytes. Release of Cu-thionein during the oxidative burst of peripheral blood monocytes Read on »
New research amid the Christmas cookies: Diabetes and immune balance by Craig At Balanced Immune Health Healthy Living Professional Posted Thu 23 Dec 2010 5:16pm on type 2 diabetes and immune balance were unveiled this week. Apparently, two types of immune cells–T-cells and monocytes– interact with each other, leading to cell and tissue... the T’s and the monocytes and help influence that balance, perhaps diabetic inflammation can be mitigated and controlled. Something to think about while keeping your holiday diet in check Read on »
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