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Melanocyte - Articles

A Transgenic Mouse Expressing Reverse Tetracycline-Controlled Transactivator in Melanocytes by nih.gov Posted Tue 15 Jun 2010 5:00pm Description of Invention: Available for licensing are transgenic mice that allow for specific and inducible expression of proteins in melanocytes. Melanocytes are difficult to study because of their paucity in mammalian skin, and these mice present a readily available source of these cells and model to study melanocyte diseases such as melanoma Read on »
Melanocyte Pigmentation or Proliferation with Neuregulin: Compositions and Methods to Treat Skin Disorders, Including Skin Canc by nih.gov Posted Wed 18 Aug 2010 5:00pm Description of Invention: Human skin pigmentation is regulated by complex and intricate interactions among melanocytes and keratinocytes in the epidermis... in expression. One among them, neuregulin 1 (NRG-1), secreted by fibroblasts derived from dark skin, effectively increases the pigmentation of melanocytes in tissue culture Read on »
Neural Crest-Melanocyte cDNA Based Microarray Analysis for Human Skin Pigmentation Research by nih.gov Posted Sat 31 Mar 2007 5:00pm and for therapeutic intervention. This invention pertains to the identification of a set of neural crest-melanocyte (NC-M) genes through microarray analysis and informatic analysis. Utilizing the extensive sequence information in the expressed sequence tag database (dbEST), the specific set of cDNA sequence was identified for microarray analysis of melanocyte function Read on »
alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse mode by Jan Posted Sun 20 Dec 2009 12:00am receptors (MC-1R) that bind alpha-melanocyte-stimulating hormone (alpha-MSH). In search of novel therapies for scleroderma (systemic sclerosis [SSc]), we used the bleomycin (BLM.... CONCLUSION: Alpha-melanocyte-stimulating hormone and related peptides that exert their effects via MC-1R may provide a novel antifibrogenic therapeutic tool for the treatment Read on »
alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse mode by Jan Posted Fri 11 Sep 2009 4:55pm receptors (MC-1R) that bind alpha-melanocyte-stimulating hormone (alpha-MSH). In search of novel therapies for scleroderma (systemic sclerosis [SSc]), we used the bleomycin (BLM.... CONCLUSION:Alpha-melanocyte-stimulating hormone and related peptides that exert their effects via MC-1R may provide a novel antifibrogenic therapeutic tool for the treatment Read on »
Experimental Drug Shows Promise in Melanoma Treatment by Northcoast Footcare Facebook Posted Sun 04 Oct 2009 11:13pm Melanoma is a cancer of melanocytes, cells that produce a pigment called melanin in the skin.  Melanoma occurs when there is a mutation within the melanocytes, causing the cells to replicate in a disorganized fashion, grow without limit, invade surrounding tissue and disrupt normal tissue function. Continue Reading » Social Bookmarking Options Read on »
Grey Matter by OnlyNatureBlog Patient Expert Posted Wed 04 Nov 2009 10:03pm be just 10 years away from coming to fruition. “When hair goes gray, there is a progressive disappearance of the melanocytes (pigment-producing cells) from the hair. While there are still melanocytes in the hair, there is still hope that it could be re-pigmented,” L’Oréal’s Patricia Pineau told the Daily Mail. Apparently, the process will involve some type Read on »
Vitiligo by Anne M. Posted Wed 12 Nov 2008 11:57pm the skin pimgentation or coloring process.  Our skin contain special cells called melanocytes which produce a substance melanin. Excess of  melanin in skin causes darken skin.  If melanocytes produce a little amount of melanin it causes  light skin. In vitiligo white patches appeare on skin.  Whereas darkening of skin due to excess of melanin is termed Read on »
What Causes Grey Hair? by Methods of Healing Patient ExpertComplimentary & Alternative Medicine Posted Wed 17 Mar 2010 9:42pm by pigmentation generated in the hair follicles called melanocytes.  The shade of hair is determined by the amount of melanin present in the hair follicles.  The more melanin present the darker the hair will be. Grey hair is attributed to the decrease of melanocytes in the hair follicles. As we age the melanocytes lose the ability to make pigment which colors our Read on »
Will Pepperie Solve My Salt and Pepper Hair? by Sarah B. Patient Expert Posted Wed 18 Nov 2009 10:00pm results when when the melanocytes in your hair follicle stop working. There are 4 different ways in which this can happen (don’t recall them exactly at the moment) but one way, the melanocytes just die and they will never come back. Another way, the melanocytes are moved out of place and they continue to work but the color never makes it into the hair Read on »