Macrophages

Silica binding and toxicity in alveolar macrophages by Jan Posted Tue 08 Dec 2009 12:00am macrophage (AM) interacts with the inhaled silica particle and the consequences of silica-induced toxicity on the cellular level. Based on experimental results, several rationales have been developed on exactly how crystalline silica particles are toxic to the macrophage cell that is functionally responsible for clearance of the foreign particle Read on »

Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscl by Cheryl Patient Expert

Posted Mon 27 Jul 2009 11:53pm Click title to read full study. Macrophagic myofasciitis (MMF) is an emerging condition of unknown cause, detected in patients with diffuse arthromyalgias and fatigue, and characterized by muscle infiltration by granular periodic acid-Schiff's reagent-positive macrophages and lymphocytes. Intracytoplasmic inclusions have been observed in macrophages Read on »

Macrophages, cancer and rejection by f1000 Posted Thu 17 Feb 2011 10:23am glycoprotein (HRG), which is secreted by the liver, has anti-tumour effects through the re-polarization of macrophages. This paper was evaluated by Guido Serini and Giulio Gabbiani , who... like a valid concern. But I don’t know much about this—immunology is generally stuff that happens to other people in my book, unless you’re talking big angry macrophages Read on »

Macrophage Migration Inhibitory Factor (MIF) by nih.gov Posted Wed 30 Apr 1997 5:00pm Description of Invention: The protein known as macrophage migration inhibitory factor (MIF) was one of the first cytokines to be discovered. Thirty-years ago it was described as a T-cell-derived factor that inhibited the random migration of macrophages in vitro. Today, MIF is known to be a mediator of the function of macrophages in host defense Read on »

Autoantibodies from mice exposed to Libby amphibole asbestos bind SSA/Ro52 – enriched apoptotic blebs of murine macrophage by Jan Posted Fri 11 Sep 2009 4:56pm apoptosis in murine macrophages as determined by phosphatidylserine exposure, cleavage of poly (ADP-ribose) polymerase and morphological changes such as nuclear condensation Read on »

Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma by Jan Posted Tue 08 Dec 2009 12:00am By Sou-Pan Wu and Colleague Objective To investigate the potential association between functional polymorphisms in the gene for the innate mediator, macrophage migration inhibitory factor (MIF), and the clinical expression of systemic sclerosis (SSc). Methods Genomic DNA samples and clinical data were collected from the Scleroderma Read on »

What goes on inside a caseating granuloma? by pathologystudent Posted Thu 10 Mar 2011 11:07am are a part of adaptive immunity. Having said that, innate immune cells (macrophages) are heavily involved. There are several steps in the process of granuloma formation in tuberculosis: 1. Initially, M. tuberculosis infections are unable to be stopped by neutrophils. So, macrophages are called in. 2. Some of the macrophages become activated because Read on »

Research shows why low vitamin D ... by Dr. Rubens D. Medical Doctor

Posted Thu 27 Aug 2009 9:32pm in vitamin D, the macrophage cells eat more cholesterol, and they can't get rid of it. The macrophages get clogged with cholesterol and become what scientists call foam cells, which... vessels and block blood flow. Bernal-Mizrachi, an assistant professor of medicine and of cell biology and physiology, studied macrophage cells taken from people with and without Read on »

TNF Response May Hold Key for Rheumatoid Arthritis by awesome Healthy Living Professional

Posted Mon 05 Apr 2010 7:00am substantial research into the early signaling pathways activated by TNF, but there is not much known about the delayed and chronic TNF responses. In addition, cells called macrophages (cells within the tissues that originate from specific white blood cells) produce TNF, but the effect of TNF on the macrophages themselves is not understood. But a study Read on »

Research may bring powerful new test for inflammatory lung diseases by COPDsurvivor Patient Expert

Posted Tue 04 Aug 2009 6:35pm irritants activate immune cells, like macrophages, in the lungs to destroy the foreign material, and chronic exposure causes inflammation. MMP12 is an enzyme secreted by macrophages... for normal wound healing. However, over-stimulation of macrophages by irritants leads to build up of excess MMP12, which starts to damage the delicate structure of the small airspaces Read on »

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