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Leishmania - Articles

TWiP 14: Leishmania by Vincent Racaniello Posted Wed 11 Aug 2010 12:00am On episode 14 of the podcast This Week in Parasitism, Vincent and Dickson consider the life cycle and pathogenesis of the protozoan parasite Leishmania. Audio clip.... tropica life cycle ( jpg ) L. major lesion ( jpg ) Transgenic mosquito delivers Leishmania vaccine (thanks, Geoffrey) Who speaks for the guinea worm ? (thanks, Michael Read on »
A New Transmission Blocking Vaccine for Leishmania Infection by nih.gov Posted Tue 16 Mar 2010 5:00pm Description of Invention: A novel transmission blocking vaccine has been developed that can eliminate or reduce the number of Leishmania chagasi parasites... of the parasite in the gut of the sand fly. This approach can effectively block Leishmania transmission to human hosts. Such vaccines have the potential to reduce the risk of humans Read on »
Vaccines Comprising Sand Fly Salivary Proteins for Control of Leishmania Infection by nih.gov Posted Tue 25 May 2010 5:00pm Description of Invention: This invention relates to the use of several peptides from the salivary glands of various sand fly species for the control of leishmania... have shown that B cell-deficient mice immunized with the plasmid vaccine also successfully controlled leishmania infection. Current in-vivo studies continue to explore the use Read on »
Leishmania in Europe by Dr. Erik McLaughlin Medical Doctor Posted Sat 13 Jun 2009 12:29am Leishmania in Europe When a group of travelers get together, there are a lot of stories and helpful tips shared. A favorite cafe, a hotel with a great location... are just hearing about leishmania for the first time, here is a quick run down: Basics: Two main types of this disease exist, cutaneous (aka Baghdad boil ) and visceral (aka Kala Read on »
Cancer Drugs May Help Stop Major Parasite by Ed H. Doctor of Pharmacy Posted Mon 02 Aug 2010 6:05pm and other disorders, researchers at Washington University School of Medicine in St. Louis have found. Scientists searched the genome of the parasite Leishmania to determine... that will inhibit them, we should be able to strike a significant blow against Leishmania,” says senior author Stephen Beverley, PhD, the Marvin A. Brennecke Professor and head of Molecular Read on »
Cancer Drugs May Help Stop Major Parasite by Ed H. Doctor of Pharmacy Posted Fri 16 Jul 2010 4:32pm Scientists at Washington University School of Medicine in St. Louis recently showed that when a key protein was genetically disabled, the parasite Leishmania couldn’t start.... Louis have found. Scientists searched the genome of the parasite Leishmania to determine that it has three kinds of TOR kinases, proteins that are linked to cell growth Read on »
Insect Salivary Proteins as Potent Adjuvants for Enhancing Immune Responses by nih.gov Posted Sun 03 May 2009 5:00pm Description of Invention: This invention relates to the discovery that specific sand fly salivary proteins have marked effects on the outcome of Leishmania... for a broad spectrum of diseases that require different immune responses. They may therefore be used to enhance immune responses to pathogens other than Leishmania parasites Read on »
Collaborative Drug Discovery by Albin P. Doctor of Pharmacy Posted Fri 12 Sep 2008 7:54am Sleeping Sickness, Chagas Disease and Leishmania. Filed under: Online Data sharing, drug development, drug discoverry, open access database, open source in biotechnoligy Read on »
Collaborative Drug Discovery by Albin P. Doctor of Pharmacy Posted Mon 29 Sep 2008 7:39pm Sleeping Sickness, Chagas Disease and Leishmania. Filed under: Online Data sharing, drug development, drug discoverry, open access database, open source in biotechnoligy Read on »
Alleviating Symptoms of Th2-Like Cytokine Mediated Disorders by Reducing IL-13 Receptor-Expressing Cells in the Respiratory Trac by nih.gov Posted Tue 15 Jun 2010 5:00pm Description of Invention: This invention relates to the alleviation of symptoms of Th2-like cytokine mediated disorders, such as allergy, asthma, and to hyperinflammatory responses in the respiratory tract to infectious diseases and parasitic infections, including tuberculosis, schistosomiasis, leishmania, and filariasis. This invention Read on »

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