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Isoflurane - Articles

Isoflurane as an Anaesthetic by Bob DeMarco Patient Expert Posted Fri 26 Mar 2010 10:41am By Max Wallack In a recent article in the Journal of Alzheimer's Disease, two Spanish researchers, Mena and Yebenese, found that a commonly used anaesthetic, Isoflurane, is safe for normal mice, but unsafe for mice that carry genetic mutations for Alzheimer's disease, even if those mice are asymptomatic. The researchers s ... Read on »
Study Reveals How Anesthetic Isoflurane Induces Alzheimer’s-Like Changes In Mammalian Brains by Ed H. Doctor of Pharmacy Posted Thu 01 Mar 2012 6:06pm The association of the inhaled anesthetic isoflurane with Alzheimer’s-disease-like changes in mammalian brains may by caused by the drug’s effects on mitochondria, the structures in which most cellular energy is produced.  In a study that will appear in Annals of Neurology and has received early online release, Massachusetts General Hospital (M ... Read on »
Study Reveals How Anesthetic Isoflurane Induces Alzheimer's-like Changes in Mammalian Brains by Susan Berg Posted Mon 19 Mar 2012 12:00am Here is a great for caregivers and healthcare professionals, You will love the Here is information on being the best caregiver you can be Here is a way for nurses administrators, social workers and other health care professionals to get an easyceu or two Follow Alzheimers1 on twitter Sciencenewsline medicine Massa ... Read on »
Common anesthetic induces Alzhei ... by Dr. Rubens D. Medical Doctor Posted Mon 17 Nov 2008 8:02pm Common anesthetic induces Alzheimer's-associated changes in mouse brains 18 nov 2008--For the first time researchers have shown that a commonly used anesthetic can produce changes associated with Alzheimer's disease in the brains of living mammals, confirming previous laboratory studies. In their Annals of Neurology report, which has received e ... Read on »
ASA Abstracts 2008 Department of Anesthesiology and Critical Care, UPENN by David Smith, MD Posted Mon 05 Oct 2009 10:03pm John G. Augoustides, Wilson Y. Szeto, Brittany Cornelius,   Elizabeth K. Walsh, Joseph E. Bavaria: Does Ischemia on Presentation Stratify Perioperative Outcome after Acute Stanford Type a Dissection? Anesthesiology 2008; A1422 Albert T. Cheung, Neil Singla, Solomon Aronson: Predicting Clevidipine Dose Requirements in Cardiac Surger ... Read on »
Recovery From Propofol Anesthesia May Be Sped By Use Of Common Stimulant by Ed H. Doctor of Pharmacy Posted Fri 06 Apr 2012 5:04pm The ability of the commonly used stimulant methylphenidate (Ritalin) to speed recovery from general anesthesia appears to apply both to the inhaled gas isoflurane, as previously reported, and to the intravenous drug propofol.  Members of the same Massachusetts General Hospital (MGH) research team that reported the isoflurane study are publishin ... Read on »
Alzheimer's and Anesthesia by Bob DeMarco Patient Expert Posted Mon 11 Jun 2012 2:37pm Alzheimer's and anesthesia don't mix well. Some physicians are advising their patients that are already diagnosed with Alzheimer’s to avoid surgery unless absolutely necessary. By Sydney S. Farrier, LCSW Sydney S. Farrier How often have you heard the comment about an older person who recently underwent ... Read on »
100 things to prevent Alzheimer's and age-related memory loss by Peter C. Complimentary & Alternative Medicine Posted Tue 04 Jan 2011 4:08pm Jean Carper has revealed in her book 100 SIMPLE THINGS YOU CAN DO TO PREVENT ALZHEIMER'S AND AGE-RELATED MEMORY LOSS (prophylactic for Alzheimer's) Among the steps that she advocated that can help people getting on in age in preventing them from catching the dreaded Alzheimer's and age-related memory loss are 1. Ask questions about anesthe ... Read on »
Refereed Publications -- Calendar Year 2008 by David Smith, MD Posted Mon 05 Oct 2009 10:03pm DEPARTMENT OF ANESTHESIOLOGY AND CRITICAL CARE UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA PA   1.         Abend NS, Huh JW, Helfaer MA, Dlugos DJ: Anticonvulsant medications in the pediatric emergency room and intensive care unit. Pediatric Emergency Care, 2008; 24: 705-18; quiz 719-21 2.         American College of ... Read on »
Inhalation anesthetics produce damage by disrupting intracellular calcium homeostasis by David Smith, MD Posted Mon 05 Oct 2009 10:03pm Huafeng Wei continues his investigations into inhaled agent toxicity.   Using chicken lymphocytes he demonstrated that isoflurane, desflurane and sevoflurane at 2 MAC for 24 hours produced cell damage by increasing cytosolic calcium.   The calcium came from the endoplasmic reticulum.   In IP3 deficient lymphocytes this damage calcium translocat ... Read on »

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