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Hepatocellular Carcinoma - Articles

Hepatocellular Carcinoma-Find out if you should be screened! by rickisjourney Posted Mon 24 May 2010 12:00am In the last few decades, the percentage of people in the United States who develop liver cancer has increased, although the rate has been relatively stable in recent years. The reason for this increase could be the increase in the number of Americans with viral hepatitis, which is known to cause hepatocellular carcinoma, the most common ... Read on »
Therapeutic Targeting of CSN5, a Negative Regulator of p53 and p27, in Human Hepatocellular Carcinoma by nih.gov Posted Fri 31 Oct 2008 5:00pm Description of Invention: Hepatocellular carcinoma (HCC) represents an extremely poor prognostic cancer that remains one of the most common and aggressive malignancies worldwide. Elevated expression of COP9 complex homolog subunit 5 (CSN5) in early HCC indicates that CSN5 is one of the early markers of malignant conversion. ... Read on »
Medical Imaging Replaces Biopsy in the Diagnosis of Hepatocellular Carcinoma by Bruce Friedman Patient Expert Posted Wed 24 Nov 2010 12:00am I believe that radiologists will soon be rendering many more definitive diagnoses than "impressions" in their reports due to improvements in imaging technology. This will place them increasingly in competition with pathologists. A recent report about the diagnosis of hepatocellular carcinoma reinforced this idea in my mind and also p ... Read on »
Methods for Determining Hepatocellular Carcinoma Subtype and Detecting Hepatic Cancer Stem Cells by nih.gov Posted Tue 31 Jul 2007 5:00pm Description of Invention: Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide, and it is very heterogeneous in terms of its clinical presentation as well as genomic and transcriptomic patterns. HCC can originate from both adult hepatocytes and hepatic progenitor cells. The extent of progenitor ... Read on »
Novel Diagnostic, Prognostic and Therapeutic Biomarker for Hepatocellular Carcinoma by nih.gov Posted Mon 26 Mar 2012 8:00pm Description of Invention: Scientists at the National Cancer Institute have discovered that Stearol-CoA desaturase-1 (SCD-1) is associated with hepatocellular carcinoma (HCC). Utilizing a microarray to analyze HCC patient samples, the investigators found SCD-1 is elevated in liver tumor tissues and it is a marker for a highly ... Read on »
CDC reports increase in hepatocellular carcinoma by Mark Pool, MD Posted Mon 10 May 2010 1:18pm The CDC reported last week in the May 7, 2010 MMR a significant increase in the incidence of cases of HCC in the U.S. over the study period from 2001-2006. To determine trends in HCC incidence in the United States, CDC analyzed data for the period 2001--2006 (the most recent data available) from CDC's National Program of Cancer Regis ... Read on »
Hepatocellular carcinoma and Folfox by Mark Levin Posted Thu 16 Dec 2010 6:04am A randomized study of Folfox was presented in the 2010 ASCO meeting. When compared with doxorubicin after 266 events, the FOLFOX4 regimen significantly improved median progression-free survival from 1.77 to 2.93 months (P = .0002) in the EACH trial. Overall survival also improved from 4.97 to 6.40 months, although the difference failed to re ... Read on »
Avastin for hepatocellular cancer by Mark Levin Posted Fri 07 Aug 2009 11:54am S D Ryder Guidelines for the diagnosis and treatment of hepatocellular carcinoma (HCC) in adults Gut 2003;52:iii1 The only proven potentially curative therapy for HCC remains surgical, either hepatic resection or liver transplantation, and patients with single small HCC ( 5 cm) or up to three lesions 3 cm should be referred for assessment fo ... Read on »
Cryosurgical ablation of hepatocullular carcinoma by Mark Levin Posted Wed 24 Jun 2009 7:01pm Cryosurgical ablation, or cryosurgery, involves freezing of target tissues, usually by inserting a probe into the tumor through which coolant is circulated. Cryosurgery may be performed as an open surgical technique or as a closed procedure under laparoscopic or ultrasound guidance. National Comprehensive Cancer Network (NCCN, 2007) hepatocellu ... Read on »
Risk Factors Relating to the Rising Trend of Hepatocellular Cancer in the U.S. by Bruce Friedman Patient Expert Posted Mon 09 Jan 2012 12:00am Hepatocellular cancer (HCC) is a common neoplasm in Asian countries because of the high incidence of hepatitis infection. Here are the three most common risk factors for (HCC):  (1) alcoholism; (2) hepatitis B; (3) hepatitis C that causes 25% of causes globally (see: Hepatocellular carcinoma ). Although HCC has been relatively rare i ... Read on »