Endothelial Cells - Articles

Sort by: Newest Most Comments Relevance

IgG antiendothelial cell autoantibodies from scleroderma patients induce leukocyte adhesion to human vascular endothelial cells by Jan Posted Mon 07 Dec 2009 12:00am D Carvalho and Colleague IgG autoantibodies that bind human endothelial cells (AECA) were detected by ELISA in 30 of 42 samples of sera from patients with scleroderma. Pretreatment of human umbilical vein endothelial cells with AECA-positive scleroderma sera, or IgG purified from these sera, led to a dose- and time-dependent increase in the ability Read on »

Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vas by Jan Posted Fri 27 Nov 2009 10:03pm to provide tools of diagnostic or pathogenetic value, putative bioindicators include anti-endothelial cell antibodies, a heterogeneous family of antibodies that react with autoantigens expressed by endothelial cells. In this study, to identify endothelial autoantigens involved in the autoimmune processes causing endothelial damage, we screened a human Read on »

Garlic inhibits free radical generation and augments antioxidant enzyme activity in vascular endothelial cells by Jan Posted Wed 18 Nov 2009 10:03pm in scavenging oxidants and preventing cell injury. Aged Garlic Extract (AGE) has been shown to prevent oxidant-induced injury of endothelial cells. The present study determined the effects of AGE on the generation of hydrogen peroxide (H2O2) and superoxide anion (O2−) and the activity of three antioxidant enzymes in bovine pulmonary artery endothelial cells Read on »

Endothelial Cells, Blood Pressure & Dark Chocolate by Cindy M. Patient Expert

Posted Mon 22 Sep 2008 11:05am ) by researchers from Yale gives the nod to dark chocolate as improving endothelial cell function and reducing blood pressure in overweight adults. For those of you who took biology many moons ago (or never), endothelial cells are critical to healthy vascular function and also play a vital role in the health and integrity of every tissue of the body! The Yale Read on »

Endothelial Cells, Blood Pressure & Dark Chocolate by Cindy M. Patient Expert

Posted Wed 22 Oct 2008 4:46pm (July 2008) by researchers from Yale gives the nod to dark chocolate as improving endothelial cell function and reducing blood pressure in overweight adults. For those of you who took biology many moons ago (or never), endothelial cells are critical to healthy vascular function and also play a vital role in the health and integrity of every tissue Read on »

The Assessment of Anti–Endothelial Cell Antibodies in Scleroderma-Associated Pulmonary Fibrosis by Jan Posted Wed 17 Nov 2010 9:13pm on samples from a control group. Western blot analysis was performed with endothelial cell protein extracts using serum samples from patients with scleroderma and from healthy... binding to proteins in extracts of human endothelial cells in all patients in whom there was evidence of pulmonary disease. The indirect immunofluorescent rodent lung assay Read on »

How does endothelial cell injury start? The role of endothelin in systemic sclerosis by Jan Posted Fri 11 Sep 2009 4:58pm processes are dysregulated in disease. In SSc, the vasculopathy is one of the earliest pathological events, characterized by endothelial cell activation and altered vascular tone... and hypoxia. This complex array of molecular interactions involves a number of cell types including the endothelial cells and their attendant perivascular supporting cells (pericytes Read on »

Effects of Flavonoid-Rich Beverages on Prostacyclin Synthesis in Humans and Human Aortic Endothelial Cells: Association with Ex by Jan Posted Thu 25 Nov 2010 7:40am synthesis. Our objective was to identify plant-derived beverages that alter synthesis of prostacyclin in cultured human aortic endothelial cells (HAEC), and to determine... and pomegranate juice increased aortic endothelial cell prostacyclin synthesis (38% and 61%, respectively; P < .05). The consumption of purple grape, pomegranate, and orange juice prolonged Read on »

Modulation of the Angiogenic Phenotype of Normal and Systemic Sclerosis Endothelial Cells by Gain-Loss of Function of Pentraxin by Jan Posted Sun 13 Mar 2011 12:26pm Objective. Studies have shown that in systemic sclerosis (SSc) endothelial cells, overproduction of matrix metalloproteinase 12 (MMP-12) and pentraxin 3 (PTX3... endothelial cells (MVECs), and whether silencing of these molecules in SSc MVECs could restore the lost angiogenic properties of the cells in vitro and in vivo. Methods Read on »

A Gene Expression Signature Identifying Pro-Angiogenic Genes in Ovarian Tumor Endothelial Cell Isolates by nih.gov Posted Thu 31 May 2007 5:00pm cells. By targeting tumor angiogenesis by inhibiting endothelial cells that support tumor growth, this technology provides methods to diagnose and ovarian cancer in its early... Publication: C Lu et al. Gene alterations identified by expression profiling in tumor-associated endothelial cells from invasive ovarian carcinoma. Cancer Res. 2007 Feb 15;67(4 Read on »