UKALL 2003 - Vincristine
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AngusPosted
Fri 12 Sep 2008 10:35am
to another of the four DNA-bases, cytosine, making Cytosine arabinoside or Ara C, and tested its anti-cancer properties with positive results.
Here's how it works (another Patty page here ).
In a cell Cytosine riboside (an RNA molecule) is converted to Cytosine deoxyribose (a DNA molecule) with the help of an enzyme. The enzyme needs to bind to the riboside
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Nexavar for Leukemia
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Mark LevinPosted
Wed 24 Jun 2009 7:01pm
. A Phase I/Phase II clinical trial for AML is open at M. D. Anderson that combines sorafenib with the standard of care chemotherapy combination for AML, idarubicin and cytosineRead on »
PTSD Risk in Women Tied to Genetics
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Jodi K.Posted
Fri 04 Mar 2011 12:40am
SNP -- called rs2267735, substituting a cytosine base for a guanine -- in men exposed to fearful situations showed no association with PTSD, the researchers also found
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Inhibition of XMRV by a weapon of mass deamination
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Vincent RacanielloPosted
Tue 20 Apr 2010 12:00am
Apobec-containing virions infect a new cell. As the viral reverse transcriptase begins to copy viral RNA into DNA, Apobec removes an amine group from cytosines in single stranded DNA, a process called deamination. The consequence of deamination is that cytosine is changed to uracil. Uracil-containing DNA may be attacked by uracil DNA glycosidase, which
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The Next Four Months - Part 2
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AngusPosted
Fri 12 Sep 2008 10:35am
drugs (Mecapturine – 6-MP, and Cytosine arabinoside – Ara-C) in the middle of the Augmented BFM phase.
Recently found an interestingpaperin the Journal of Clinical Oncology
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FLAM for AML
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Mark LevinPosted
Fri 07 Aug 2009 11:54am
. Smith, M. J. Levis, S. D. Gore, J. Greer, C. Hattenburg, J. Briel, R. J. Jones, J. J. Wright, and A. D. Colevas
Sequential Flavopiridol, Cytosine Arabinoside, and Mitoxantrone
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ASHAP for salvage for Hodgkin's
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Mark LevinPosted
Sun 15 Nov 2009 10:02pm
= cytosine arabinoside, and Platinum = cisplatinum) which appears to provide a similar response rate to that of other chemo regimens. A similar regimen, ESHAP, is more established
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Resveratrol: the red wine magic chemical
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Bill KlemmPosted
Fri 02 Apr 2010 12:00am
was a little misleading, in that there was a "ceiling effect" in that the young adults, even though given cytosine, were already performing at near-mazimum levles. Cytosine had clear
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ADHD gene #6. Serotonin receptor 1B gene (HTR1B)
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Nicolas I.Posted
Thu 22 Jan 2009 6:54pm
), some individuals have a DNA base of "G" (short for "Guanine"), while others have the DNA base of "C" (short for "Cytosine", for more info on what this means, please click here
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Epigenetics and Addiction
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Dirk H.Posted
Mon 21 Jul 2008 10:18am
to cytosine in the DNA base, effectively turning genes on or off without making major alterations to genetic structure. (Gene mutations or insertions, on the other hand, are capable
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