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Cyclosporin - Articles

Generic cyclosporin is bioequivalent to Neoral. by Mark Levin Posted Sun 04 Oct 2009 11:12pm Neoral® is indicated for the prophylaxis of organ rejection in kidney, liver, and heart allogeneic transplants. Neoral® has been used in combination with azathioprine and corticosteroids. Food and Drug Administration (FDA) has approved their AB-rated generic equivalent of Novartis Pharmaceuticals' Neoral, the biggest selling softgel immunosuppr ... Read on »
Cyclosporine in Membranous Nephropathy: A non-immune modulatory effect to maintain remission? by Matt S. Posted Tue 27 Apr 2010 12:00am This is the story of a 64 year old male mason with past medical history notable for hypertension and hyperlipidemia who was referred to me for evaluation of proteinuria. The patient noted onset of lower extremity edema nine months prior to the clinic visit. At the time, he was admitted to the hospital due to increasing complaints of lowe ... Read on »
cyclosporine ophthalmic ointment by Visiocare Posted Mon 12 Jul 2010 9:52pm Cyclosporine is used for the treatment of Keratoconjuctivitis sicca & CSK in dogs. Visiocare is a new branded generic in the market. Which has same effective as main brand Optimmune.  Optimmune is highly expensive as compared to Visiocare. Visiocare has same effectivenes for the treatment of "Dry Eye" in dogs. Due to dry eye dog may loss his vision ... Read on »
New Mechanism for Cyclosporin in Proteinuric Disease by Matt S. Posted Fri 10 Oct 2008 12:00am Cyclosporin A (CsA) has been a mainstay of therapy for nephrologists: it (along with tacrolimus) has become the cornerstone of immunosuppressant therapy for kidney transplant patients; in addition, it has also seen use as an effective agent in proteinuric disease states such as membranous nephropathy, FSGS, and minimal change disease. The ... Read on »
cyclosporine versus tacrolimus by Matt S. Posted Sun 26 Jul 2009 12:00am The two calcineurin inhibitors routinely used for kidney transplant immunosuppression are cyclosporine (CSA) and tacrolimus (TAC).  Their mechanism of action is somewhat similar (they both inhibit calcineurin, which under normal circumstances induces transcription of IL-2 in lymphocytes) but they get there by different routes:  CSA binds cyc ... Read on »
Response of aplastic anaemia and scleroderma to cyclosporin by Jan Posted Wed 13 Oct 2010 12:00am Summary Scleroderma and aplastic anaemia (AA) occurred simultaneously in a patient. Treatment with antilymphocyte globulin (ALG) resulted in some improvement of the scleroderma and a partial, temporary response of the AA. Both the scleroderma and AA then responded dramatically to cyclosporin (CSA) therapy. Subsequently, a positive Ham' ... Read on »
Bedtime reading: drug safety update Ciclosporin by Dr. Donal O'Donoghue Patient Expert Posted Wed 09 Dec 2009 12:00am Ciclosporin must be prescribed and dispensed by brand name. The medicines and healthcare products regulatory agency issued a drug safety update at the beginning of December emphasising the importance of prescribing and dispensing Ciclosporin by name. Ciclosporin has a narrow therapeutic index which means that the dose has to be very carefully a ... Read on »
The dawn that wasn't - Part 4 by Kamal S. Patient ExpertHealth Maven Posted Sat 23 Aug 2008 10:48pm An important part of a transplant is the post surgery medication. This involves a set of medicines including immunosuppresants and steroids. Basically these medicines prevent rejection of the new organ by the body. Cyclosporin is the most commonly used immunosuppresant. Unfortunately, in Hemolytic Uremic Syndrome (HUS), cyclosporin is su ... Read on »
The call by Kamal S. Patient ExpertHealth Maven Posted Sun 24 Aug 2008 2:57pm It was midnight last night when my cell phone rang. I had fallen asleep about half an hour back while waiting for my tech, Jairam to come and start dialysis. We've changed the cannulation sites and so he's been doing the cannulation for a few days now. I had called him around 10:30 and he said he would be late because he was caught up in ... Read on »
IBD by nitinsyal Patient Expert Posted Thu 25 Jun 2009 9:53pm Inflammatory bowel disease (IBD) is an idiopathic disease, probably involving an immune reaction of the body to its own intestinal tract. The 2 major types of IBD are ulcerative colitis and Crohn disease. As the name suggests, ulcerative colitis is limited to the colon; Crohn disease can involve any segment of the gastrointestinal tract from the ... Read on »