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Cell Mediated Immune Reaction - Articles

The endothelium: its role in scleroderma by Jan Posted Wed 18 Nov 2009 10:03pm Altered blood vessel, or vascular, activity and anatomy is one of the problems associated with the development of systemic sclerosis, or scleroderma. Damage and dysfunction of endothelial cells, which form the smooth lining of blood vessels, seem to be a primary event. Formerly, these cells were thought to be inactive or to have the function o ... Read on »
The Four Types of Immune Sensitivity Reactions & Renal Examples for Each by Matt S. Posted Wed 12 Aug 2009 12:00am Basic Clinical Immunology:  there are four types of hypersensitivity reactions.  Below is a listing of all four types and, since this is a Nephrology Blog, renal examples for each one. Type I Immune Reaction (anaphylactic):  Type I hypersensitivity reactions are IgE-mediated responses which occur relatively rapidly following ex ... Read on »
Yervoy (ipilimumab): Risk Evaluation and Mitigation Strategy (REMS) - Severe Immune-Mediated Adverse Reactions by FDA Posted Wed 06 Apr 2011 11:00am [Posted 04/06/2011] AUDIENCE: Hematology-Oncology ISSUE: Bristol-Myers Squibb informed healthcare professionals about the risk evaluation and mitigation strategy (REMS), developed in collaboration with FDA, that is required to ensure that the benefits of Yervoy outweigh the risks of severe and fatal immune-mediated ... Read on »
FcepsilonRI -Bearing Human Mast Cell Lines by Posted Thu 31 Oct 2002 4:00pm Description of Invention: Allergic diseases, which include asthma, are a significant health problem in the United States, with 15-25% of the population displaying some form of allergies. The mast cell is the major effector cell of allergic inflammation and has also been shown to be involved in delayed hypersensitivity reaction ... Read on »
Are all autoimmune diseases caused by hypersensitivity reactions? by pathologystudent Posted Thu 06 Jan 2011 3:51pm From time to time, I get questions regarding the connection between hypersensitivity reactions and autoimmune diseases. We discuss them one after the other in class – so it makes sense to try to sort out how they are related. Here are a couple recent questions: Q. My question is: which of the four hypersensitivity reactions are consi ... Read on »
Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vas by Jan Posted Fri 27 Nov 2009 10:03pm By Paola Margutti and Colleague Although detection of autoantibodies in the peripheral blood from patients with immune-mediated endothelial dysfunctions has so far failed to provide tools of diagnostic or pathogenetic value, putative bioindicators include anti-endothelial cell antibodies, a heterogeneous family of antibodies that react with aut ... Read on »
The relationship of defective cell-mediated immunity to visceral disease in systemic sclerosis. by Jan Posted Fri 11 Sep 2009 4:57pm By P. Hughes and Colleague Phytohaemagglutinin-induced lymphocyte transformation and circulating thymus-dependent (T) lymphocyte numbers were studied in twenty-eight patients with systemic sclerosis (SS), in fifty normal controls and eleven elderly controls. Patients with SS were found to have impaired lymphocyte transformation responses wh ... Read on »
Why Food Allergies May Be Making You Sick by Mark Hyman, M.D. Medical Doctor Posted Mon 22 Sep 2008 11:06am 5 Comments Could you be allergic to specific foods and not even know it? Could a hidden allergic response to food be responsible for depression, ADHD, obesity, migraines, irritable bowel syndrome, joint pains, arthritis, and many other common conditions that resist treatment by conventional approaches? Nowhere in medicine is there more controversy, su ... Read on »
Getting rid of prostate symptoms in men is very hard and the much harder part is getting effective prostate cures by winter1101 Posted Sun 12 May 2013 12:12pm It still remains something of a mystery as to how local bacterial control is lost in the immunocompromised patient. Chlamydia tests. Bacterial Persistence: Pro- and Anti-Inflammatory Response Clincal and in vitro studies related to the Lyme disease co-infection Bartonella implicated a Th1 immune response. The old Bartonella skin test required ... Read on »
Know on Celluar imune by Merrilee Fullerton Medical Doctor Posted Tue 12 Jun 2012 10:04pm Cellular immune reactions include several phenomena in which T cells play a pivotal role. Examples are delayed hypersensitivity reactions, resistance against infection by certain bacteria and viruses, rejection of solid organ transplants, and resistance against tumors. Regulatery fu-notions. T cells perform important functions in modulati ... Read on »