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Causes Of Chronic Myeloid Leukemia - Articles

The Faulty Gene Behind Chronic Myeloid Leukemia by CancerTeam .. Posted Sun 24 Aug 2008 1:49pm ANNOUNCER: Scientists today know a great deal about chronic myeloid leukemia. The story of their research into the disease goes back 40 years, to a lab in Philadelphia. Peter Nowell at the University of Pennsylvania stumbled on a technique to make the chromosomes of dividing cells visible under the microscope. Nowell showed slides of chromosomes fr ... Read on »
If chronic myeloid leukemia is a chronic leukemia, why does it have immature cells? by pathologystudent Posted Wed 19 May 2010 5:31pm Q. If the chronic leukemias have lots of mature cells, and the acute leukemias have immature cells, then how come chronic myeloid leukemia has lots of immature cells? Seems like it belongs in the acute leukemia category! A. I think the best way to look at it is to oversimplify it a little, to get at the basics, and then put in a litt ... Read on »
Trials Point to More Treatment Options for Chronic Myeloid Leukemia by Cancer.gov Posted Wed 07 Jul 2010 9:00pm Trials Point to More Treatment Options for Chronic Myeloid Leukemia Adapted from the NCI Cancer Bulletin, vol. 7/no. 12, June 15, 2010 ( see the current issue ). Short-term results from two phase III clinical trials suggest that patients with chronic myeloid leukemia (CML) may have new o ... Read on »
Monitoring Therapy in Chronic Myeloid Leukemia by CancerTeam .. Posted Sun 24 Aug 2008 1:49pm ANNOUNCER: Treatment of chronic myeloid leukemia begins with bringing blood counts back to normal. BRIAN DRUKER, MD: When a person is diagnosed with CML, they often will have as many as one trillion leukemia cells. Their white count is 5 to 50 times the upper limit of normal. If we can lower their blood counts to normal, we say that that's a com ... Read on »
New Treatment for chronic myeloid leukemia by Katherine B. Patient Expert Posted Thu 28 May 2009 11:24pm The FDA has approved Sprycel (dasatinib) for use in the treatment of adults in all phases of chronic myeloid leukemia (CML) with resistance or intolerance to prior therapy including Gleevec. Like Gleevec, Sprycel is very expensive. Gleevec can cost $35,000 dollars a year. The price of Sprycel, an oral medication, varies by dosage but the price ... Read on »
Experimental Drug Effective for Chronic Myeloid Leukemia by Medline Plus Posted Tue 04 Dec 2012 10:21am Source: American Cancer Society Related MedlinePlus Page: Chronic Myeloid Leukemia Read on »
Gleevec for bcr/abl negative chronic myelogenous leukemia, by Mark Levin Posted Wed 01 Feb 2012 4:41am The diagnosis of chronic myelogenous leukemia (CML) consists of a complete blood count with differential, peripheral blood smear, and bone marrow analysis. Although typical hepatomegaly and splenomegaly may be imaged by using a liver/spleen scan, these abnormalities are often so obvious clinically that radiologic imaging is not necessary. Th ... Read on »
Big Pimpin' by EthidiumBromide Medical Student Posted Thu 09 Apr 2009 7:16pm Today in the clinical cancer center, I got pimped. Or, I suppose more like – I became a participant in the pimping process. I know you’re all thinking, “But Julie, why is that worthy of writing about? How is that any different from your normal activities?” Alas, that certainly is the crowd I roll with on the weekends (as long as my biochemi ... Read on »
CML Therapy Update by CancerTeam .. Posted Sun 24 Aug 2008 1:49pm JOHN GOLDMAN, MD: The story of imatinib, as it's unfolded, has really been very exciting. If you go back ten years, we had nothing really to offer a patient other than interferon, which was complicated, or bone marrow transplant, which was very dangerous. And then in 1998, for the first time we were able to use this new agent which rapidly becam ... Read on »
Are chronic myeloproliferative disorders really leukemias? by pathologystudent Posted Wed 12 May 2010 8:01am Q. I was wondering what the difference was between labeling something as a “leukemia” vs labeling it as a “chronic myeloproliferative disorder.” I understand that leukemias are neoplastic proliferations of hematopoietic stem cells in the bone marrow, but aren’t myeloproliferative disorders the same thing? In particular, what category wou ... Read on »