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Biomarker Test - Articles

Penn Medical Pathologists Pioneer Biomarker Test to Diagnose or Rule Out Alzheimer’s Disease by Bob DeMarco Patient Expert Posted Thu 02 Apr 2009 12:53pm Penn Medicine Pathologists Pioneer Biomarker Test to Diagnose or Rule Out Alzheimer’s Disease Biomarker Signatures Predict Conversion from Mild Cognitive Impairment to Alzheimer... and track the progression of Alzheimer’s disease,” said Dr. Shaw. “Validated biomarker tests will improve the focus of Alzheimer’s clinical trials, enrolling patients at earlier Read on »
Blood Biomarker Test Assesses Heart Failure Risk by WorldHealth.net Posted Mon 29 Nov 2010 9:01pm | Certain measures of the blood biomarker cardiac troponin T (cTnT), a cardiac-specific protein, using a highly sensitive test, are associated with the development of heart failure... Heart Failure and Cardiovascular Mortality in Older Adults.”  JAMA, Nov 2010; doi:10.1001/jama.2010.1708. Blood Biomarker Test Assesses Heart Read on »
A Collaborative Effort to Find Biological Markers by The Myelin Repair Foundation Posted Wed 18 Aug 2010 8:00am Neil Buckholtz, chief of the Dementias of Aging Branch at the National Institute of Aging, in the National Institutes of Health. The New York Times reports on a successful collaboration , the Alzheimer’s Disease Neuroimaging Initiative, which created a platform for sharing data on the biological markers (or biomarkers) of Alzheimer Read on »
Alzheimer's Disease, Biological Markers, and the Collaboration of Mankind by Bob DeMarco Patient Expert Posted Fri 13 Aug 2010 7:26am emission tomography (PET), other biological markers, and clinical and neuropsychological assessment can be combined to measure the progression of mild cognitive impairment (MCI) and early Alzheimer’s disease (AD). In other words, to learn more about Alzheimer's disease, how it unfolds in the brain, and to discover biological markers that indicate probable Read on »
biologic markers can change after metastasis by Donna Peach Patient Expert Posted Mon 20 Sep 2010 12:00am Researchers note that the three biologic markers in breast cancer (estrogen, progesterone and HER2) may change when breast cancer metastasizes, particularly with liver metastases. The conclusion, thus, is that, in cases of liver mets, it may be a good idea … Continue reading → Read on »
Researchers Discover Possible Biological Marker For Depression by Jeremiah D. Doctor of Philosophy Posted Fri 03 Oct 2008 12:52pm This article reviews a recent finding that there may be a quick way to biologically assess whether an individual has depression, and (possibly more importantly), whether a particular antidepressant treatment is the "right fit" for that particular individual.  Money quote: "We discovered that in depressed individuals a signaling protein is ... Read on »
Save Unnecessary Thyroid Surgery with new Afirma Molecular Marker Test by Dr. Richard Guttler Medical Doctor Posted Wed 05 Jan 2011 12:00am Well thyroid patients heading to elective surgery for suspicious but not positive diagnosis of thyroid cancer, there is now a test, Afirma that can save you and 35,000 others this year from that surgery. It is a marker test with 143 genes, that if present on a 2 pass ultrasound guided FNA will give you a 96% chance it is benign. This is good Read on »
PETACC-3 study and correlation of molecular markers with stage-specific prognosis by Mark Pool, MD Posted Wed 06 May 2009 12:00am and molecular testing from 1404 patients with stage II/III cancer in a substudy to correlate various markers with stage-specific prognosis.  The markers evaluated included p53, SMAD4... from this substudy is strikingly different changes in marker expression between the two groups.  This suggests that stage II and stage III CRC develop through distinctly Read on »
Molecular Markers Linked to Deat ... by Dr. Rubens D. Medical Doctor Posted Wed 06 May 2009 12:28pm Molecular Markers Linked to Death From Prostate Cancer Cancer patients with bcl-2, p53, high microvessel density had higher risk of cancer death 06 may 2009... on clinical practice for several reasons," write the authors of an accompanying editorial, pointing out that "the hazard ratios are of insufficient magnitude for the markers Read on »
Molecular markers for targeted therapy in lung cancer: USCAP 2010 by Mark Pool, MD Posted Fri 26 Mar 2010 8:04am and one of the leaders in the field of molecular pathology of lung cancer.  The title of his presentation was "Molecular Predictive Markers for Targeted Therapies in Lung Cancer... are insufficient to exclude EGFR mutation testing.  Thus, every adenocarcinoma should be tested for EGFR mutation (with the exception of mucinous ACa/BAC which are always KRAS mutants Read on »