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Ugly Cell: Diffuse Large B-Cell Lymphoma in the Brain by Dr. Brian M. Medical DoctorHealth Maven Posted Mon 26 Jan 2009 3:49pm A 69-year-old woman presented with a brain mass that was thought to be a primary brain tumor. Instead, our diagnosis turned out to be Diffuse Large B-Cell Lymphoma, Anaplastic Type. This is not a lymphoma that is restricted to the central nervous system; but thus far in this patient the malignancy has only shown up in the brain. A representative ph ... Read on »
Just how many B-cell lymphomas are there? by pathologystudent Posted Thu 14 Apr 2011 7:34pm Q. Can you explain a bit about the classification of B-cell lymphoma? I’m a teacher, and I’ve inherited a lecture on lymphomas. The previous lecturer’s PowerPoint says there are three types of B-cell lymphoma: 1. Small-cell B-cell lymphoma, 2. Large-cell B-cell lymphoma, and 3. Mixed cell type B-cell lymphoma. Have the names of these subt ... Read on »
Revlimid for refractory relapsed B-cell lymphoma by Mark Levin Posted Wed 24 Jun 2009 7:01pm Revlimid is promising for CLL. Revlimid is an orally administered derivative of thalidomide, which is a very active agent for the treatment of multiple myeloma but has serious side effects, especially thromboembolism. Revlimid is reported to have less toxicity than thalidomide but retains antimyeloma effects. Revlimid has recently been appro ... Read on »
Mediastinal large B-cell lymphoma associated with systemic sclerosis by Jan Posted Mon 21 Dec 2009 10:17pm Malignant lymphoma (ML) is frequently associated with several forms of collagen diseases such as Sjören syndrome, systemic lupus erythematodes, and rheumatoid arthritis. However, the occurrence of ML in systemic sclerosis (SSc) patients has rarely been reported. Here we report an SSc patient who developed mediastinal (thymic) large B-cell lym ... Read on »
Treating Lymphoma: Will a Customized Vaccine Work? by CancerTeam .. Posted Sun 24 Aug 2008 1:49pm ANNOUNCER: Non-Hodgkin's Lymphoma is the sixth most common cause of death from cancer. It's a disease where certain cells in the immune system grow uncontrolled. JOHN LEONARD, MD: The cells of the immune system typically have a job to do to fight infections. And in lymphoma the switches that regulate the cell's growth are broken, and the cells ac ... Read on »
NIH scientists identify possible gene target for treating a form of lymphoma by Cancer.gov Posted Wed 22 Dec 2010 12:00am NIH scientists identify possible gene target for treating a form of lymphoma Researchers have identified a mutation in a gene that could lead to targeted therapies for certain lymphoma patients whose cure rates are currently poor. Mutation of the MYD88 gene was found to be one of the most frequent genetic abnormalities in a form ... Read on »
NIH scientists identify possible gene target for treating a form of lymphoma by Cancer.gov Posted Thu 10 Mar 2011 9:59pm NIH scientists identify possible gene target for treating a form of lymphoma Researchers have identified a mutation in a gene that could lead to targeted therapies for certain lymphoma patients whose cure rates are currently poor. Mutation of the MYD88 gene was found to be one of the most frequent genetic abnormalities in a form of ca ... Read on »
Dose-adjusted Chemotherapy for Untreated c-MYC-positive Lymphomas by Cancer.gov Posted Tue 25 Jan 2011 12:00am Dose-adjusted Chemotherapy for Untreated c-MYC-positive Lymphomas Name of the Trial Phase II Study of Dose-Adjusted EPOCH-Rituximab in Adults with Untreated Burkitt Lymphoma and c-MYC+ Diffuse Large B-Cell Lymphoma (NCI-10-C-0052). See the protocol summary . Principal Investi ... Read on »
Part 3. Molecular testing in lymphoma: USCAP 2010 by Mark Pool, MD Posted Mon 26 Apr 2010 8:00am Final recap from Dr. Adam Bagg's lecture at USCAP 2010 on molecular testing in lymphoma.  The highpoint of the lecture for me was his comments on diffuse large B-cell lymphoma (DLBCL) since this is the most common lymphoma type we see in our practice.  It so happens that there have been some recent papers that I've read that complement Dr. B ... Read on »
Lymphocyte-rich vs. lymphocyte predominance Hodgkin lymphoma by pathologystudent Posted Mon 16 Jun 2014 10:50pm   Q. I’m working on getting all of these lymphomas straight in my head. I was wondering if you could elaborate on the differences between nodular lymphocyte predominance and the “classical” Hodgkin lymphomas. Specifically, I can’t easily differentiate between nodular lymphocyte predominance Hodgkin and lymphocyte-rich Hodgkin lym ... Read on »