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Angiotensin Ii - Articles
Basic Review: The Renin-Angiotensin-Aldosterone Axis
by
Matt S.
Posted
Thu 27 Aug 2009 12:00am
.
Angiotensin I is cleaved to form angiotensin II by angiotensin converting enzyme (ACE), which is found predominantly within lung endothelium. ACE-inhibitors, as their name implies, targets the ACE enzyme and is one of the most potent anti-hypertensives (and GFR-preserving) therapies available.
Angiotensin II has the following physiologic effects, which
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A trap for angiotensin type 1 receptors
by
Matt S.
Posted
Sat 13 Mar 2010 12:00am
The renin-angiotensin system is powerful regulator of blood pressure homeostasis. An article published in the March 24 issue of JASN highlights an emerging area of research into the modulation of AT1 receptors on different tissues.
The majority of well-known angiotensin II actions are mediated via AT1 receptor stimulation, and angiotensin
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Angiotensin receptor blocker candesartan helps prevent diabetic retina problems
by
Dr. John Z.
Posted
Tue 02 Mar 2010 12:00am
- angiotensin receptor blockers - may be useful in preventing and treating diabetic retinopathy, the leading cause of vision loss in people with diabetes. The study, the largest to date... inhibitors and angiotensin receptor blockers (ARBs), may help prevent the condition.
The scientists analyzed proteins from the retinas laboratory mice with normal blood pressure
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Key to angiotensin formation solved? Preeclampsia linked to oxidative stress
by
Matt S.
Posted
Fri 08 Oct 2010 1:00am
Researchers from the UK published a new and exciting article exploring one of the fundamental mechanisms of blood pressure regulation by the renin-angiotensin-system (RAS... here for a review of the RAS from Nate). The first step of this process is the cleavage of angiotensinogen by the enzyme renin to form angiotensin I (Ang I). Precisely how renin
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Angiotensin-Receptor Blocker of ...
by
Dr. Rubens D.
Posted
Sat 15 Nov 2008 7:54pm
Angiotensin-Receptor Blocker of No Benefit in Patients with Heart Failure, Preserved Systolic Function
16 nov 2008--The angiotensin-receptor blocker irbesartan does... in patients with heart failure and preserved systolic function. There is currently no indication for an angiotensin-receptor blocker in these patients."
LINK(S):
NEJM article
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Brown rice, cardiovascular protection, and angiotensin II
by
Dr. John Z.
Posted
Thu 29 Apr 2010 12:00am
angiotensin II. Angiotensin II is an endocrine protein and a known culprit in the development of high blood pressure and atherosclerosis. Considering this angiotensin II inhibition, brown rice may ultimately become known as a functional food for people at risk for high blood pressure.
Brown Rice and Angiotensin II Inhibition
The subaleurone layer
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Angiotensin Receptor Blockers (ARBs): Ongoing Safety Review for Cancer Risk
by
FDA
Posted
Thu 15 Jul 2010 11:10am
[Posted 07/15/2010]
AUDIENCE: Cardiology, Oncology, Family Practice
ISSUE: A recently published study - a meta-analysis combining cancer-related findings from several clinical trials - suggested use of ARBs may be associated with a small increased risk of cancer.
BACKGROUND: ARBs are used in patients with high ...
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Aliskiren
by
Matt S.
Posted
Tue 29 Apr 2008 12:00am
converting enzyme-catalyzing of angiotensin I to angiotensin II, is the rate-limiting step in the pathway.
... of angiotensin converting enzyme (ACE) or the angiotensin receptor (ARB), a new class of direct renin inhibitors of which aliskiren is the current prototype are now being tested. While
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