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Anesthetics Inhalational - Articles

Inhalation anesthetics produce damage by disrupting intracellular calcium homeostasis by David Smith, MD Posted Mon 05 Oct 2009 10:03pm Huafeng Wei continues his investigations into inhaled agent toxicity.   Using chicken lymphocytes he demonstrated that isoflurane, desflurane and sevoflurane at 2 MAC for 24 hours produced cell damage by increasing cytosolic calcium.   The calcium came from the endoplasmic reticulum.   In IP3 deficient lymphocytes this damage calcium translocat ... Read on »
Pet Anesthetic by heru m. Patient Expert Posted Mon 20 Dec 2010 7:11am Before the anesthetic procedure A thorough history of current and past medical problems can provide valuable information about your pet’s physical condition. A history of poor ability to exercise may indicate abnormal heart or lung function, an important consideration when planning an anesthetic procedure. Physical examinati ... Read on »
Study Shows Inhaled Anesthesia Affects Children’s Brains More Than Intravenous Anesthetic by Ed H. Doctor of Pharmacy Posted Fri 26 Oct 2012 10:37pm Stony Brook University School of Medicine researchers have found that children’s brains are more affected by an inhaled anesthetic than an intravenous anesthetic with increased levels of brain lactate. Lactate increases brain activation and may lead to metabolic changes associated with anxiety and delirium. Reported in the November issue of Ane ... Read on »
Consensus Statement – First international workshop on anesthetics and Alzheimer’s disease by David Smith, MD Posted Mon 05 Oct 2009 10:03pm The workshop was held in May, 2008 at the University of Pennsylvania and the consensus document was recently published in Anesthesia and Analgesia.   The statement provides 8 conclusions: 1) The benefits of general anesthetics in allowing surgery and other painful procedures likely outweighs the potentially toxic effects that are currently know ... Read on »
Alzheimer's and Anesthesia by Bob DeMarco Patient Expert Posted Mon 11 Jun 2012 2:37pm Alzheimer's and anesthesia don't mix well. Some physicians are advising their patients that are already diagnosed with Alzheimer’s to avoid surgery unless absolutely necessary. By Sydney S. Farrier, LCSW Sydney S. Farrier How often have you heard the comment about an older person who recently underwent ... Read on »
Study Reveals How Anesthetic Isoflurane Induces Alzheimer's-like Changes in Mammalian Brains by Susan Berg Posted Mon 19 Mar 2012 12:00am Here is a great for caregivers and healthcare professionals, You will love the Here is information on being the best caregiver you can be Here is a way for nurses administrators, social workers and other health care professionals to get an easyceu or two Follow Alzheimers1 on twitter Sciencenewsline medicine Massa ... Read on »
Study Reveals How Anesthetic Isoflurane Induces Alzheimer’s-Like Changes In Mammalian Brains by Ed H. Doctor of Pharmacy Posted Thu 01 Mar 2012 6:06pm The association of the inhaled anesthetic isoflurane with Alzheimer’s-disease-like changes in mammalian brains may by caused by the drug’s effects on mitochondria, the structures in which most cellular energy is produced.  In a study that will appear in Annals of Neurology and has received early online release, Massachusetts General Hospital (M ... Read on »
Refereed Publications -- Calendar Year 2008 by David Smith, MD Posted Mon 05 Oct 2009 10:03pm DEPARTMENT OF ANESTHESIOLOGY AND CRITICAL CARE UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA PA   1.         Abend NS, Huh JW, Helfaer MA, Dlugos DJ: Anticonvulsant medications in the pediatric emergency room and intensive care unit. Pediatric Emergency Care, 2008; 24: 705-18; quiz 719-21 2.         American College of ... Read on »
Obstetrics for cardiologists ! by Dr. Sangareddi V. Medical Doctor Posted Thu 12 Aug 2010 9:41am Cardiologist are often confronted with pregnant women in distress with heart disease. Obstetricians promptly refer them to cardiologists. There is a tendency among cardiologists,  to make fun of obstetricians who  some times  call them for  frivolous  cardiac problem at odd hours  .(Say a VPD in the monitor or a systolic murmur of anemia et ... Read on »
Malignant Hyperthermia confirmed in Florida Plastic Surgery death by Dr. Robert O. Medical Doctor Posted Fri 11 Jul 2008 5:11pm An autopsy has confirmed that the South Florida teenager,Stephanie Kuleba, who died this Spring after corrective breast surgery (reportedly for significant asymmetry and inverted nipples) suffered from a rare genetic disease that had been speculated to have causes her death. Genetic testing at the University of Pittsburgh shows she possessed the ... Read on »