Beta-2 Microglobulin Amyloidosis
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Matt S.Posted
Wed 06 Aug 2008 12:00am
The two major forms of amyloidosis are AL amyloidosis (in which light chains form the amyloid deposits) and AA amyloidosis (in which a variety of inflammatory molecules may adopt a beta-pleated structure to deposit as amyloid.
A specific subset of AA amyloidosis which is secondary to dialysis is beta-2 microglobulin amyloidosis. Beta-2
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New Therapies for Systemic Amyloidosis
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Matt S.Posted
Wed 14 Jan 2009 12:00am
Systemic amyloidosis can involve nearly any organ, and the kidney is often involved. Recall that there are two flavors of amyloidosis: AL amyloidosis (in which the amyloid is formed by light chains as a result of a paraproteinemia) or AA amyloidosis (in which a chronic inflammatory condition, such as rheumatoid arthritis, leads to the excess
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Sudden Cardiac Death in Infiltrative Cardiomyopathies: Sarcoidosis, Scleroderma, Amyloidosis, Hemachromatosis
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JanPosted
Fri 27 Nov 2009 10:03pm
By S. Lubitz, S. Goldbarg, D. Mehta
Sarcoidosis, scleroderma, amyloidosis, and hemachromatosis are systemic infiltrative disorders that commonly affect the heart. Owing to their potential for diffuse organ involvement, these diseases may present with myriad clinical manifestations.
Conduction system abnormalities are common, and each of these disorders has
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Digital Case Challenge: Pleuropulmonary amyloidosis
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Mark Pool, MDPosted
Wed 26 May 2010 12:52pm
and polarization (below).
Pulmonary Amyloidosis
Pulmonary amyloidosis includes a spectrum of clinicopathologic entities that commonly have deposition of amorphous, eosinophilic... with pulmonary amyloidosis:
Systemic or Generalized
Limited or Localized
Diffuse Alveolar Septal
Pleural
Systemic amyloidosis may be primary (idiopathic) and associated
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Hereditary Amyloidosis
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Matt S.Posted
Tue 17 Jun 2008 12:00am
fever (FMF) or Muckle-Wells Syndrome, and the reason these individuals may get renal disease is due to AA amyloidosis. Patients with TRAPS can (logically enough) be treated
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Fecal transmission of AA amyloidosis in the cheetah contributes to high incidence of disease
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Terry S.Posted
Sun 07 Sep 2008 2:06am
Fecal transmission of AA amyloidosis in the cheetah contributes to high incidence of disease
Beiru Zhang*†, Yumi Une‡, Xiaoying Fu*, Jingmin Yan*, FengXia Ge*, Junjie Yao... Institutes of Health, Bethesda, MD, and approved April 1, 2008 (received for review January 16, 2008)
AA amyloidosis is one of the principal causes of morbidity and mortality
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Progression from SMM to MM
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MargaretPosted
Fri 04 Sep 2009 10:59pm
A study published in The New England Journal of Medicine this month (the abstract can be read at: http://tinyurl.com/yweyh9) looks at the risk of progression from SMM (or smoldering or inactive or asymptomatic myeloma) to symptomatic MM or amyloidosis. Digression: have you ever had an amyloidosis test? I have, and I must say that I [...]
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October 15, 2009 - Day 178
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dezwitPosted
Thu 15 Oct 2009 10:03pm
If you don't have Amyloidosis, thank your God everyday.
If you do have it, you know what I am talking about.
Sorry, that's it for today, a bad one at best.
Will write tomorrow.
Goodnight
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The past week has been very diff ...
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Dr. KevinPosted
Fri 16 Oct 2009 10:04pm
. If this is only caused by a virus, then I should improve. But if the bowel problems are from amyloidosis, I may never get better. You can imagine what that feels like when the proximity... I heard 'amyloidsosis'. I was quite pleased that someone thought of it. The physician told me after that he once had cared for a patient with renal amyloidosis. At least
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Splenomegaly: an(other) approach to its causes (2)
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JeremyPosted
Fri 28 Aug 2009 8:18pm
.
Splenomegaly II: By aetiology
Infectious - CMV, EBV, HIV, endocarditis, TB, malaria, schistosomiasis, leishmaniasis, histoplasmosis
Inflammatory - sarcoid, amyloidosis
Neoplastic..., splenic vein obstruction, haemoglobinopathies, nutritional anaemias
(OK, I know you might have quibbles shoehorning "amyloidosis" into the 'inflammatory' heading, but it saves
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