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Aldosterone Uses - Articles

Glucocorticoid-Remediable Aldosteronism by Matt S. Posted Thu 01 May 2008 12:00am Glucocorticoid-Remediable Aldosteronism (GRA) is an inherited autosomal dominant disorder which causes early-onset (often childhood) high blood pressure, often occuring in individuals with Celtic ancestry. It typically presents with standard symptoms of aldosteronism (hypertension, hypokalemia, and metabolic alkalosis) with a high aldostero ... Read on »
The Aldosterone Antagonist Eplerenone in Populations with Heart Failure: Another Task for Disease Management Programs by JaanS Medical Doctor Posted Sun 14 Nov 2010 3:13pm After the Disease Management Care Blog read this New England Journal of Medicine report back in 1999, it began to prescribe the aldosterone antagonist " spironolactone " for its patients with low ejection fraction chronic heart failure. Aldosterone is one of many normal human hormones that increase in response to a struggling heart. High levels ... Read on »
Why doesn’t aldosterone secretion depend on ACTH? by pathologystudent Posted Sun 13 Feb 2011 5:23am Q. I have a question about the secretion of aldosterone that I haven’t been able to figure out by searching online or looking in books (maybe I’m looking in the wrong places!). My question stems from my understanding that aldosterone is one of the end products in the pathway starting with cholesterol.  We learned from you, and other pr ... Read on »
Electrolyte Channels and Aldosteronism by Matt S. Posted Wed 26 Jun 2013 12:00am Over the past few years, it has become apparent that hyperaldosteronism is far commoner than was once suspected and screening of unselected patients with hypertension reveals that about 5-10% of patients have primary hyperaldosteronism. In patients with resistant hypertension, that percentage increases to 15-20%. About 30% of hyperaldosteroni ... Read on »
Aldosterone: the hormone we never knew we had by Flower Spy Posted Wed 12 Nov 2008 12:00am Aldosterone is being over produced in my left adrenal. I had no idea what it was until I was diagnosed with this disease back in July. Wanting to learn as much as I could about this weirdly named hormone, I did some research to find out what its role was in my adrenals and what happens when too much of it is being produced. The definition: Al ... Read on »
Basic Review: The Renin-Angiotensin-Aldosterone Axis by Matt S. Posted Thu 27 Aug 2009 12:00am One of the coolest aspects of the renin-angiotensin-aldosterone system (RAAS) is that it involves multiple organ systems: the liver, lung, adrenal gland, kidney, and vasculature are all prominently involved. It never hurts to review basic physiologic principles, right? Listed are the three main components of the RAAS and their main mechan ... Read on »
Evaluation of primary aldosteronism: seeing is not believing by Matt S. Posted Wed 02 Feb 2011 5:00am As you would have likely guessed by looking at the picture to the  left we often tend to believe what we see without giving much thought.  This is frequently true in the evaluation and management of patients with primary aldosteronism (PA) where the diagnostic tests are frequently misinterpreted and findings on imaging studies such as CT and MRI ... Read on »
From the RFN Archives: Glucocorticoid-Remediable Aldosteronism by Matt S. Posted Mon 19 Sep 2011 6:15pm Glucocorticoid-Remediable Aldosteronism (GRA) is an inherited autosomal dominant disorder which causes early-onset (often childhood) high blood pressure, often occuring in individuals with Celtic ancestry. It typically presents with standard symptoms of aldosteronism (hypertension, hypokalemia, and metabolic alkalosis) with a high aldoster ... Read on »
A critical approach to management of Refractory cardiac failure ! by Dr. Sangareddi V. Medical Doctor Posted Sun 15 Jul 2012 11:30am Caution: This is a fairly lengthy article . Optimal Reading time  15  minutes Cardiac failure is a progressive systemic disease  ,  even though the primary problem originates in the heart .Most of the symptoms and clinical features are related to Neuro-Endocrine activation instigated by poor pumping function.When the diminishing cardiac ... Read on »
Your Dehydroepiandrosterone (DHEA) and Magnesium levels basically determine your present state of health. by Stephen Tvedten Patient Expert Posted Tue 29 Dec 2009 12:00am 1 Comment Your Dehydroepiandrosterone (DHEA) and Magnesium levels basically determine your present state of health. Unfortunately, the majority of Americans lose 80-90% of their optimal DHEA between ages 30 and 80. According to Dr. Norman Shealy, every known illness is associated with a magnesium deficiency and low levels of the hormone DHEA. D ... Read on »