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High-level Expression and Purification of Untagged and Histidine-tagged Human Immunodeficiency Virus type-1 (HIV-1) Reverse Tran by Posted Sun 13 Jun 2010 5:00pm Description of Invention: This invention includes plasmids and protocols to express and purify large quantities of histidine-tagged and untagged HIV-1 reverse transcriptase (RT). Conditions have been optimized for overexpression and purification of p66 and p51 heterodimer RT in E. coli. High-level of expression was reached a ... Read on »
FDA approves first rapid diagnostic test to detect both HIV-1 antigen and HIV-1/2 antibodies by Health & Human Services Posted Thu 08 Aug 2013 5:25pm By Cross-posted from FDA News Release The U.S. Food and Drug Administration today approved the first rapid Human Immunodeficiency Virus (HIV) test for the simultaneous detection of HIV-1 p24 antigen as well as antibodies to both HIV-1 and HIV-2 in human serum, plasma, and venous or fingerstick whole blood specimens. Approved for ... Read on »
The Influence of Viral Factors on Long-term Nonprogressing HIV by Dave W. Doctor of PhilosophyHealth Maven Posted Wed 22 Oct 2008 4:32pm The progression of HIV infection varies from one individual to another. Although “the median time from infection to development of AIDS is 8 to 10 years,” some individuals, known as long-term nonprogressors, fail to develop AIDS after infection with HIV (Hogan and Hammer, 2001). These individuals have been identified on various continents, and ... Read on »
Intersecting Epidemics: HIV/AIDS and Tuberculosis by Dave W. Doctor of PhilosophyHealth Maven Posted Sat 17 Oct 2009 10:00pm Hi, I’m Justin Eusebio. While tuberculosis is one of the world’s oldest surviving plagues and HIV-1 infection is one of medicine’s newest challenges, there is an undeniable relationship between HIV/AIDS and tuberculosis. Independently, Mycobacteria tuberculosis and HIV are formidable pathogens but in concert, the prospects for controlling eit ... Read on »
Combined HIV Antibody/Antigen Test Approved by Paul Sax Posted Wed 23 Jun 2010 8:10am From the FDA : The U.S. Food and Drug Administration today approved the first assay to detect both antigen and antibodies to Human Immunodeficiency Virus (HIV)… The highly sensitive assay is intended to be used as an aid in the diagnosis of HIV-1/HIV-2 infection, including acute or primary HIV-1 infection. Since it actually detects the HI ... Read on »
Taking Lessons from the CCR5Δ32 Mutation for Patient Treatment by Dave W. Doctor of PhilosophyHealth Maven Posted Fri 20 Nov 2009 10:00pm I’m Lindsay Sween, and welcome to this installment of the AIDS Pandemic blog and podcast. Human immunodeficiency virus type 1 (HIV-1) invades a CD4+ (T4) cell through the attachment of the viral protein gp120 to its primary cellular receptor, CD4, and to a transmembrane chemokine coreceptor, usually CCR5 or CXCR4. Agrawal et al. (2007) explain ... Read on »
Plant Extract Inhibits HIV-1 by A4M Posted Thu 13 Feb 2014 10:08pm Posted on Feb. 12, 2014, 6 a.m. in HIV and AIDS Botanical Agents Geranium - image from Shutterstock According to the World Health Organization (WHO) ... Read on »
Hepatoma Cell Line That Can Be Infected with Both Hepatitis C and Human Immunodeficiency (HIV-1) Viruses by Posted Sun 20 Jun 2010 5:00pm Description of Invention: It is estimated that 250,000 HIV patients in the U.S. are chronically infected with hepatitis C virus (HCV). Co-infection of HCV and HIV is associated with increased morbidity and mortality relative to mono-infection with either virus. Compared to HCV mono-infected individuals, HCV/HIV co-infected in ... Read on »
Methods for Treating Drug-Resistant HIV-1 Infection by Posted Sun 13 Jun 2010 5:00pm Description of Invention: Drug-resistance is a critical factor contributing to the loss of clinical benefit of currently available human immunodeficiency virus-1 (HIV-1) therapies. Accordingly, combination therapies have evolved to address the rapidly evolving virus. However, there has been great concern regarding the growin ... Read on »
Food Security and HIV/AIDS in Kenya by Kelly Moltzen Posted Sun 09 May 2010 12:00am Ellen Gustafson, the co-founder of FEED Projects , launched the " 30 Project " on TEDxEast this past Friday. In light of reading the statistics on the new 30 Project website (namely, "The U.S. now spends 20 times more on food aid to Africa than it does helping Africans develop ways to feed themselves," I've decided to post a paper I wrote last ... Read on »