ANNOUNCER: You may not know the term NSAIDs, but you do know what they're commonly used for: relief of everyday pain.
BYRON CRYER, MD: NSAIDs stands for non-steroidal anti-inflammatory drugs. These are pain medicines that are commonly taken for conditions such as headaches or arthritis or various aches and pains. They are available in various forms. You can get them over-the-counter or you can get them by prescription.
ANNOUNCER: And while NSAIDs are a common sight in many medicine cabinets, they are still drugs and their use can create problems.
C. MEL WILCOX, MD: The most common side effect that we would see from NSAIDs are vague abdominal symptoms. But we know that patients can develop significant abdominal problems such as a bleeding ulcer or even perforation, which is a hole in the stomach related to NSAIDs which would require surgery.
ANNOUNCER: Often these side effects occur without warning.
GEORGE TRIADAFILOPOULOS, MD: One of the unfortunate issues with these drugs is that sometimes you may have absolutely no warning sign. Up to 80 percent, in one of our studies; 80 percent of people who ended up actually being admitted to the hospital and suffering major gastrointestinal complications had no warning sign that would have alerted their physicians to the possibility that they would get into trouble down the line.
ANNOUNCER: Frequently people put themselves at risk by taking more than the recommended dose of these medicines
BYRON CRYER, MD: Overusage of NSAIDs is a huge part of the problem and overusage manifests itself in a number of ways. For example, patients may take a greater number of capsules or tablets than indicated on the label or the prescription. Or they may take their dose at a time just before they're supposed to take it. Or they may take a greater number of doses per day. Or they may take various forms of NSAIDs in combination.
ANNOUNCER: Too often people are combining more than one NSAID medication without knowing it.
GEORGE TRIADAFILOPOULOS, MD: A lot of them are available over-the-counter. Therefore, patients may pick them up from the pharmacy without a prescription, use them as they wish, and sometimes, patients have already a prescription NSAID, given to them by their doctor, and then they add an additional one.
BYRON CRYER, MD: Physicians see this in their practice every day. About a third of the patients who are receiving a prescription for an NSAID are also concurrently taking another form of NSAID. Typically the physician is unaware of this combination and the patient is unaware of this problem.
ANNOUNCER: Avoiding trouble begins with being a smart consumer.
BRYRON CRYER, MD: The various reasons it's important to read the label of either the prescription or the over-the-counter product is to figure out, is to know, how many times per day one should take the medicines. To know at what dosage interval one should take the medicines. To know what ingredients are within the medicine.
There are not a lot of NSAIDs that are available over the counter. There are only four: aspirin, ibuprofen, ketoprofen and naproxen. And so if you can remember those four medications and read all of the over-the-counter ingredients and over-the-counter products for one of those ingredients, it should be easy to know whether or not you're putting yourself at risk.
ANNOUNCER: Being aware of NSAID- related risks can be made much easier by consulting with health care professionals.
C. MEL WILCOX, MD: A lot of pharmacists now can give you information on the specific medication that you're taking so that you can realize if you are taking one of these NSAIDs. They also can tell you if the medication that you buy in the drug store over-the-counter may interact with the medications that you're already taking.
GEORGE TRIADAFILOPOULOS, MD: It is quite important to let your physician know about other drugs that are used. Many times there is a risk of combining two different classes of drugs that have the same damaging effect on the stomach. Therefore, it is very important to let your doctor know that, "Yes, I'm using aspirin," or, "No, I'm not." Or "Yes, I'm using this drug over-the-counter," or "No, I'm not," before your doctor can decide about what drug to prescribe.
ANNOUNCER: In the end the patient has to be the one who understands the potential for a problem.
C. MEL WILCOX, MD: The main thing people need to know about NSAIDs is that these are very effective drugs for amelioration of pain, but also there is a lot of misunderstanding that these drugs are safe. These drugs are safe. But if you take them in increased dosages or when you combine them with other medications that you're already taking, they can be dangerous. So education is very critical.
BYRON CRYER, MD: NSAIDs stands for non-steroidal anti-inflammatory drugs. These are pain medicines that are commonly taken for conditions such as headaches or arthritis or various aches and pains. They are available in various forms. You can get them over-the-counter or you can get them by prescription.
ANNOUNCER: And while NSAIDs are a common sight in many medicine cabinets, they are still drugs and their use can create problems.
C. MEL WILCOX, MD: The most common side effect that we would see from NSAIDs are vague abdominal symptoms. But we know that patients can develop significant abdominal problems such as a bleeding ulcer or even perforation, which is a hole in the stomach related to NSAIDs which would require surgery.
ANNOUNCER: Often these side effects occur without warning.
GEORGE TRIADAFILOPOULOS, MD: One of the unfortunate issues with these drugs is that sometimes you may have absolutely no warning sign. Up to 80 percent, in one of our studies; 80 percent of people who ended up actually being admitted to the hospital and suffering major gastrointestinal complications had no warning sign that would have alerted their physicians to the possibility that they would get into trouble down the line.
ANNOUNCER: Frequently people put themselves at risk by taking more than the recommended dose of these medicines
BYRON CRYER, MD: Overusage of NSAIDs is a huge part of the problem and overusage manifests itself in a number of ways. For example, patients may take a greater number of capsules or tablets than indicated on the label or the prescription. Or they may take their dose at a time just before they're supposed to take it. Or they may take a greater number of doses per day. Or they may take various forms of NSAIDs in combination.
ANNOUNCER: Too often people are combining more than one NSAID medication without knowing it.
GEORGE TRIADAFILOPOULOS, MD: A lot of them are available over-the-counter. Therefore, patients may pick them up from the pharmacy without a prescription, use them as they wish, and sometimes, patients have already a prescription NSAID, given to them by their doctor, and then they add an additional one.
BYRON CRYER, MD: Physicians see this in their practice every day. About a third of the patients who are receiving a prescription for an NSAID are also concurrently taking another form of NSAID. Typically the physician is unaware of this combination and the patient is unaware of this problem.
ANNOUNCER: Avoiding trouble begins with being a smart consumer.
BRYRON CRYER, MD: The various reasons it's important to read the label of either the prescription or the over-the-counter product is to figure out, is to know, how many times per day one should take the medicines. To know at what dosage interval one should take the medicines. To know what ingredients are within the medicine.
There are not a lot of NSAIDs that are available over the counter. There are only four: aspirin, ibuprofen, ketoprofen and naproxen. And so if you can remember those four medications and read all of the over-the-counter ingredients and over-the-counter products for one of those ingredients, it should be easy to know whether or not you're putting yourself at risk.
ANNOUNCER: Being aware of NSAID- related risks can be made much easier by consulting with health care professionals.
C. MEL WILCOX, MD: A lot of pharmacists now can give you information on the specific medication that you're taking so that you can realize if you are taking one of these NSAIDs. They also can tell you if the medication that you buy in the drug store over-the-counter may interact with the medications that you're already taking.
GEORGE TRIADAFILOPOULOS, MD: It is quite important to let your physician know about other drugs that are used. Many times there is a risk of combining two different classes of drugs that have the same damaging effect on the stomach. Therefore, it is very important to let your doctor know that, "Yes, I'm using aspirin," or, "No, I'm not." Or "Yes, I'm using this drug over-the-counter," or "No, I'm not," before your doctor can decide about what drug to prescribe.
ANNOUNCER: In the end the patient has to be the one who understands the potential for a problem.
C. MEL WILCOX, MD: The main thing people need to know about NSAIDs is that these are very effective drugs for amelioration of pain, but also there is a lot of misunderstanding that these drugs are safe. These drugs are safe. But if you take them in increased dosages or when you combine them with other medications that you're already taking, they can be dangerous. So education is very critical.