It can take 4-12 weeks for an antidepressant to become effective, Amanda. They may make anxiety worse in the initial few weeks. Also, while no antidepressant is intrinsically better than the others, one or two often are for an individual. Unfortunately, there is no way of predicting which it will be. It may take 2 or 3 attempts to find the most effective one for a patient.
Small doses of a benzodiazepine such as alprazolam (Xanax) or diazepam (Valium) for a week or two can help during the transition phase. However, some doctors are reluctant to prescribe these because of the perceived dependency issue.
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