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By Neil Kao

Specialty: Allergy & Immunology

Blog: http://kaoallergyasthma.blogspot.com

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Drug Update: New Medications 2012

Posted Dec 31 2012 12:00am

1. ProAir HFA will begin to become available with a counter for the number of doses of albuterol remaining located in the actuator during January of 2013.

2.

3. Combivent Respimat will replace Combivent inhalers. The new device does not use a propellent. 4. Sanofi will launch a new product named Auvi-Q for delivering epinephrine subcutaneously for anaphylaxis. This has a recording to guide its use which will be activated when the cover is removed. The cost has not been announced yet. Insurance coverage during the first year will not likely be good. For comparison, Epi-pen 2-pack retails for $309 at CVS, when I checked last week. My inspection showed a well designed product. 5. Consumers may have noticed when they go to pick up Singulair at the drug store or receive mail order, they are given its generic montelukast. 6. Gastrocrom is an oral preparation of cromolyn sodium and is indicated for mastocytosis. This is a disease where mast cells release histamine in potentially fatal amounts. The cost for a group of 96 unit dose ampules ranges from $459-1,000. I did not know the cost previously. 7. Aerospan is flunisolide HFA 80 mcg and indicated for "maintenance treatment of asthma as prophylactic therapy in adult and pediatric patients 6 years of age and older". This Forest Pharmaceutical product was approved 1/26/06 by the FDA . The label change was approved on 11/16/12. No word currently from the new owner Action Pharmaceuticals.
8. Tudorza is an orally inhaled dry powder of aclidinium which was approved by the FDA on 7/23/2012 . Aclidinium inhibits the M3 receptor so it is classified as an antimuscarinic, which are in turn grouped as anticholinergic. This compound produces long-acting bronchodilation in patients with COPD. Tudorza has not been launched yet.
9. Generic Clarinex (desloratadine) was approved during the summer . I just got confirmation from some patients that this given to them for refills, not the name brand. Even recently, insurance companies have been pushing back to have the patient switched to a generic medication. Note this means that there no oral name-brand only antihistamines available by either OTC or prescription now.

The Allergy Dude wishes you a Happy New Year!!

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