From Geriatric Pharmacy Intern: Yaneya Armas, PharmD (c). Palm Beach Atlantic University School of Pharmacy
CoQ-10 (Co-enzyme Q10) is a naturally occurring antioxidant that can be found in the cells of the human body. The heart, liver, and kidneys have the highest concentrations. Its antioxidant effects might have potential benefits for cardiovascular as well as non-cardiovascular diseases such as congestive heart failure, hypertension, angina, and periodontal disease. CoQ-10 can be predominantly found in fish, nuts, and meat. Cereals, vegetables and dairy products contain lower levels of this compound. The exact amount required to attain the potential benefits of CoQ-10 is controversial. Some studies have suggested up to 600 mg of CoQ-10 daily for the treatment of angina and 150 mg in divided doses daily for the treatment of congestive heart failure. The amount recommended for hypertension is 100 mg once a day and 25 mg twice a day for periodontal disease. CoQ-10 is commercially available in a variety of formulations with a wide dosage range from 10 to 300 mg. Regardless of the alleged benefits of this compound; further studies are needed to establish optimal doses in different conditions as well as potential drug-drug interactions. Always consult with your doctor or pharmacist before adding any over the counter medication or supplement to your prescription regimen.